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ALDH7A1 aldehyde dehydrogenase 7 family, member A1 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001182 Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001201377 Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
NM_001202404 Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol ALDH7A1
Entrez Gene ID 501
Full Name aldehyde dehydrogenase 7 family, member A1
Synonyms ATQ1, EPD, FLJ11738, FLJ92814, PDE
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011].

MIM: 107323

Epilepsy, pyridoxine-dependent, 266100 (3)

mRNA Protein Product Sequence Price Select
NM_001182, 319655559 NP_001173, 188035924 alpha-aminoadipic semialdehyde dehydrogenase isoform 1 precursor ORF Sequence $550.00
NM_001201377, 319655560 NP_001188306, 319655561 alpha-aminoadipic semialdehyde dehydrogenase isoform 2 ORF Sequence $360.00
NM_001202404, 320202963 NP_001189333, 320202964 alpha-aminoadipic semialdehyde dehydrogenase isoform 3 ORF Sequence $550.00
hsa00071Fatty acid metabolism
hsa00280Valine, leucine and isoleucine degradation
hsa_M00135GABA biosynthesis, eukaryotes, putrescine => GABA
hsa00010Glycolysis / Gluconeogenesis
hsa00340Histidine metabolism
hsa00561Glycerolipid metabolism
hsa00640Propanoate metabolism
hsa00310Lysine degradation
hsa00260Glycine, serine and threonine metabolism
hsa00380Tryptophan metabolism
hsa00330Arginine and proline metabolism
hsa00300Lysine biosynthesis
hsa00410beta-Alanine metabolism
hsa00053Ascorbate and aldarate metabolism
hsa_M00032Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
hsa00620Pyruvate metabolism
HUMAN_LYSINE-DEG1-PWYlysine degradation II
REACT_1298Lysine catabolism
REACT_13Metabolism of amino acids and derivatives
Homo sapiens (human)ALDH7A1NP_001173.2
Pan troglodytes (chimpanzee)ALDH7A1XP_001157473.2
Macaca mulatta (Rhesus monkey)ALDH7A1XP_001095681.2
Canis lupus familiaris (dog)ALDH7A1XP_538607.2
Bos taurus (cattle)ALDH7A1NP_001039434.2
Mus musculus (house mouse)Aldh7a1NP_613066.2
Rattus norvegicus (Norway rat)Aldh7a1XP_214535.3
Gallus gallus (chicken)ALDH7A1XP_424422.2
Danio rerio (zebrafish)aldh7a1NP_997889.1
Drosophila melanogaster (fruit fly)CG9629NP_649099.1
Caenorhabditis elegansalh-9NP_498263.2
Arabidopsis thaliana (thale cress)ALDH7B4NP_849807.1
GeneCards ALDH7A1
UniProt P49419
MIM 107323
Ensembl ENSG00000164904
HGNC 877
HPRD 00124

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
alpha-aminoadipic semialdehyde dehydrogenase
alpha-aminoadipic semialdehyde dehydrogenase
P6c dehydrogenase
alpha-AASA dehydrogenase
26g turgor protein homolog
betaine aldehyde dehydrogenase
delta1-piperideine-6-carboxylate dehydrogenase


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