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OTX2 orthodenticle homeobox 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001270523 Homo sapiens orthodenticle homeobox 2 (OTX2), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $449.00 14
NM_001270524 Homo sapiens orthodenticle homeobox 2 (OTX2), transcript variant 4, mRNA. GenEZ ORF Cloning On-demand $449.00 14
NM_001270525 Homo sapiens orthodenticle homeobox 2 (OTX2), transcript variant 5, mRNA. GenEZ ORF Cloning In-stock $348.00 $299.00 10
NM_021728 Homo sapiens orthodenticle homeobox 2 (OTX2), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $348.00 $299.00 10
NM_172337 Homo sapiens orthodenticle homeobox 2 (OTX2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $449.00 14

*Business Day

Related Services

Gene Symbol OTX2
Entrez Gene ID 5015
Full Name orthodenticle homeobox 2
Synonyms MCOPS5, MGC45000
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q22.3

Summary This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012].
Disorder

MIM: 600037

Microphthalmia, syndromic 5, 610125 (3)

mRNA Protein Product Sequence Price Select
NM_001270523, 395455070 NP_001257452, 395455071 homeobox protein OTX2 isoform b ORF Sequence $300.00
NM_001270524, 395455072 NP_001257453, 395455073 homeobox protein OTX2 isoform b ORF Sequence $300.00
NM_001270525, 395455074 NP_001257454, 395455075 homeobox protein OTX2 isoform a ORF Sequence $199.00
NM_021728, 395455068 NP_068374, 11119420 homeobox protein OTX2 isoform a ORF Sequence $199.00
NM_172337, 395455069 NP_758840, 27436933 homeobox protein OTX2 isoform b ORF Sequence $300.00
WikiPathways
WP1742TP53 network
Homo sapiens (human)OTX2NP_068374.1
Pan troglodytes (chimpanzee)OTX2XP_001163043.2
Canis lupus familiaris (dog)OTX2XP_003435187.1
Bos taurus (cattle)OTX2NP_001180130.1
Mus musculus (house mouse)Otx2NP_659090.1
Rattus norvegicus (Norway rat)Otx2NP_001094036.1
Gallus gallus (chicken)OTX2NP_989851.2
Danio rerio (zebrafish)otx2NP_571326.1
GeneCards OTX2
UniProt F1T0D0, P32243, F1T0C9, F1T0D1
MIM 600037
Ensembl ENSG00000165588
HGNC 8522
HPRD 07190

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
homeobox protein OTX2
Names
homeobox protein OTX2
orthodenticle homolog 2

Interactant



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