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Sequence in raw or FASTA format:

Database:

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OXCT1 3-oxoacid CoA transferase 1 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000436 Homo sapiens 3-oxoacid CoA transferase 1 (OXCT1), nuclear gene encoding mitochondrial protein, mRNA. ORF Sequence $453.27
Peptide Services
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Gene Symbol OXCT1
Entrez Gene ID 5019
Full Name 3-oxoacid CoA transferase 1
Synonyms OXCT, SCOT
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5p13.1

Summary This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008].
Disorder

MIM: 601424

Succinyl CoA:3-oxoacid CoA transferase deficiency, 245050 (3)

mRNA Protein Product Sequence Price Select
NM_000436, 112382246 NP_000427, 4557817 succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial precursor Full Length $1250.20
ORF Sequence $453.27
KEGG
hsa00650Butanoate metabolism
hsa00280Valine, leucine and isoleucine degradation
hsa00072Synthesis and degradation of ketone bodies
WikiPathways
WP311Synthesis and Degradation of Ketone Bodies
BIOCYC
META_PWY66-368ketolysis
HUMAN_PWY66-368ketolysis
Reactome
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_1861Ketone body metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_59Utilization of Ketone Bodies
Homo sapiens (human)OXCT1NP_000427.1
Pan troglodytes (chimpanzee)OXCT1XP_001137948.1
Macaca mulatta (Rhesus monkey)OXCT1XP_001087834.1
Canis lupus familiaris (dog)OXCT1XP_536487.2
Bos taurus (cattle)OXCT1NP_001069538.1
Mus musculus (house mouse)Oxct1NP_077150.1
Rattus norvegicus (Norway rat)Oxct1NP_001121052.1
Gallus gallus (chicken)OXCT1NP_001006578.2
Danio rerio (zebrafish)oxct1aNP_001007292.1
Danio rerio (zebrafish)oxct1bNP_001070618.1
Drosophila melanogaster (fruit fly)CG1140NP_647683.1
Caenorhabditis elegansC05C10.3NP_496144.1
GeneCards OXCT1
PDB 3DLX
UniProt P55809
MIM 601424
Ensembl ENSG00000083720
HGNC 8527
HPRD 02001

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
Names
succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
SCOT-s
3-oxoacid CoA-transferase 1
3-oxoacid-CoA transferase 1
succinyl CoA:3-oxoacid CoA transferase
succinyl-CoA:3-ketoacid-CoA transferase
somatic-type succinyl CoA:3-oxoacid CoA-transferase
somatic-type succinyl-CoA:3-oxoacid CoA-transferase
somatic-type succinyl-CoA:3-oxoacid-CoA-transferase
succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
NP_000427.1

Interactant

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