• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


POLR1D polymerase (RNA) I polypeptide D, 16kDa [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu16733 NM_015972 Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu16955 NM_152705 Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant 2, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu18322 NM_001206559 Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant 3, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu16733 XM_005266412 PREDICTED: Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu16955 XM_005266414 PREDICTED: Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu16733C NM_015972 Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00
OHu16955C NM_152705 Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant 2, mRNA. Customized vector In-stock 5-7 $149.00
OHu18322C NM_001206559 Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant 3, mRNA. Customized vector In-stock 5-7 $149.00
OHu16733C XM_005266412 PREDICTED: Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant X1, mRNA. Customized vector On-demand 7-9 $209.00
OHu16955C XM_005266414 PREDICTED: Homo sapiens polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant X3, mRNA. Customized vector On-demand 7-9 $209.00

*Business Day

Related Services

Gene Symbol POLR1D
Entrez Gene ID 51082
Full Name polymerase (RNA) I polypeptide D, 16kDa
Synonyms AC19, POLR1C, RPA16, RPA9, RPAC2, RPC16, RPO1-3, TCS2
General protein information
Preferred Names
DNA-directed RNA polymerases I and III subunit RPAC2
Names
DNA-directed RNA polymerases I and III subunit RPAC2
RNA polymerases I and III subunit AC2
DNA-directed RNA polymerase I subunit D
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

13

13q12.2

Summary The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011].
Disorder

MIM: 613715

Treacher Collins syndrome 2, 613717 (3)

mRNA Protein Product Sequence Price Select
NM_001206559, 330864728 NP_001193488, 330864729 DNA-directed RNA polymerases I and III subunit RPAC2 isoform 3 ORF Sequence $99.00
NM_015972, 330864725 NP_057056, 7705740 DNA-directed RNA polymerases I and III subunit RPAC2 isoform 1 ORF Sequence $99.00
NM_152705, 330864727 NP_689918, 22749407 DNA-directed RNA polymerases I and III subunit RPAC2 isoform 2 ORF Sequence $99.00
XM_005266412, 530402410 XP_005266469, 530402411 DNA-directed RNA polymerases I and III subunit RPAC2 isoform X1 ORF Sequence $150.00
XM_005266414, 530402414 XP_005266471, 530402415 DNA-directed RNA polymerases I and III subunit RPAC2 isoform X3 ORF Sequence $150.00
KEGG
hsa00240Pyrimidine metabolism
hsa00230Purine metabolism
hsa03020RNA polymerase
hsa04623Cytosolic DNA-sensing pathway
hsa_M00181RNA polymerase III, eukaryotes
hsa_M00182RNA polymerase I, eukaryotes
hsa05169Epstein-Barr virus infection
WikiPathways
WP405Eukaryotic Transcription Initiation
WP231TNF-alpha/NF-kB Signaling Pathway
Reactome
REACT_71Gene Expression
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_2204RNA Polymerase I Chain Elongation
REACT_1913RNA Polymerase I Promoter Escape
REACT_1074RNA Polymerase I Transcription Termination
REACT_1371RNA Polymerase III Transcription
REACT_1974RNA Polymerase I Promoter Clearance
REACT_281RNA Polymerase III Transcription Initiation
REACT_953RNA Polymerase I Transcription Initiation
REACT_571RNA Polymerase III Transcription Initiation From Type 3 Promoter
REACT_756RNA Polymerase III Chain Elongation
REACT_1309RNA Polymerase I Transcription
REACT_347RNA Polymerase III Transcription Initiation From Type 1 Promoter
REACT_1036RNA Polymerase III Transcription Initiation From Type 2 Promoter
REACT_63RNA Polymerase III Transcription Termination
REACT_22339RNA Polymerase III Abortive And Retractive Initiation
REACT_21352RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_118823Cytosolic sensors of pathogen-associated DNA
REACT_200834Negative epigenetic regulation of rRNA expression
REACT_200857Epigenetic regulation of gene expression
REACT_200856NoRC negatively regulates rRNA expression
Homo sapiens (human)POLR1DNP_057056.1
Pan troglodytes (chimpanzee)POLR1DXP_003952423.1
Macaca mulatta (Rhesus monkey)POLR1DXP_001110871.1
Canis lupus familiaris (dog)POLR1DXP_003433343.1
Bos taurus (cattle)POLR1DNP_001069612.1
Mus musculus (house mouse)Polr1dNP_033113.1
Gallus gallus (chicken)POLR1DXP_426271.2
Danio rerio (zebrafish)polr1dNP_001003888.1
Drosophila melanogaster (fruit fly)l(2)37CgNP_001260563.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100495369XP_002937095.1
Process
IDNameEvidence
GO:0006360transcription from RNA polymerase I promoterTAS
GO:0006361transcription initiation from RNA polymerase I promoterTAS
GO:0006362transcription elongation from RNA polymerase I promoterTAS
GO:0006363termination of RNA polymerase I transcriptionTAS
GO:0006383transcription from RNA polymerase III promoterTAS
GO:0006385transcription elongation from RNA polymerase III promoterTAS
GO:0006386termination of RNA polymerase III transcriptionTAS
GO:0010467gene expressionTAS
GO:0032481positive regulation of type I interferon productionTAS
GO:0045087innate immune responseTAS
Component
IDNameEvidence
GO:0005654nucleoplasmTAS
GO:0005666DNA-directed RNA polymerase III complexIBA
GO:0005736DNA-directed RNA polymerase I complexIBA
GO:0005829cytosolTAS
Function
IDNameEvidence
GO:0001054RNA polymerase I activityIBA
GO:0001056RNA polymerase III activityIBA
GO:0003677DNA bindingIEA
GO:0046983protein dimerization activityIEA
GeneCards POLR1D
UniProt Q9Y2S0
Vega OTTHUMG00000016635
MIM 613715
Ensembl ENSG00000186184
HGNC 20422
HPRD 17877

Related articles in PubMed

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.