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PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001040633 Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant c, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_016203 Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a, mRNA. GenEZ ORF Cloning On-demand $849.00 20
NM_024429 Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant b, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

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Gene Symbol PRKAG2
Entrez Gene ID 51422
Full Name protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Synonyms AAKG, AAKG2, CMH6, H91620p, WPWS
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7q36.1

Summary AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602743

Wolff-Parkinson-White syndrome, 194200 (3); Cardiomyopathy,

mRNA Protein Product Sequence Price Select
NM_001040633, 100913191 NP_001035723, 100913192 5'-AMP-activated protein kinase subunit gamma-2 isoform c ORF Sequence $550.00
NM_016203, 100913190 NP_057287, 33186925 5'-AMP-activated protein kinase subunit gamma-2 isoform a ORF Sequence $700.00
NM_024429, 100913188 NP_077747, 100913189 5'-AMP-activated protein kinase subunit gamma-2 isoform b ORF Sequence $269.00
KEGG
hsa04920Adipocytokine signaling pathway
hsa04910Insulin signaling pathway
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa04710Circadian rhythm
WikiPathways
WP1541Energy Metabolism
WP1403AMPK signaling
WP1471TOR signaling
Reactome
REACT_6838mTOR signalling
REACT_22258Metabolism of lipids and lipoproteins
REACT_1195Insulin receptor signalling cascade
REACT_1988AMPK inhibits chREBP transcriptional activation activity
REACT_111217Metabolism
REACT_456PKB-mediated events
REACT_976PI3K Cascade
REACT_111102Signal Transduction
REACT_498Signaling by Insulin receptor
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_147867Translocation of GLUT4 to the Plasma Membrane
REACT_11123Membrane Trafficking
REACT_332IRS-mediated signalling
REACT_21285Regulation of AMPK activity via LKB1
REACT_1505Integration of energy metabolism
REACT_21393Regulation of Rheb GTPase activity by AMPK
REACT_21387Energy dependent regulation of mTOR by LKB1-AMPK
REACT_11082Import of palmitoyl-CoA into the mitochondrial matrix
REACT_762IRS-related events
Homo sapiens (human)PRKAG2NP_057287.2
Pan troglodytes (chimpanzee)PRKAG2XP_003318972.1
Canis lupus familiaris (dog)PRKAG2XP_532769.3
Mus musculus (house mouse)Prkag2NP_663376.2
Rattus norvegicus (Norway rat)Prkag2NP_908940.1
Gallus gallus (chicken)PRKAG2NP_001026136.1
Danio rerio (zebrafish)zgc:153329NP_001070647.1
Drosophila melanogaster (fruit fly)SNF4AgammaNP_001163672.1
GeneCards PRKAG2
UniProt Q9UGJ0
MIM 602743
Ensembl ENSG00000106617
HGNC 9386
HPRD 04119

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
5'-AMP-activated protein kinase subunit gamma-2
Names
5'-AMP-activated protein kinase subunit gamma-2
AMPK subunit gamma-2

Interactant



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