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Sequence in raw or FASTA format:

Database:

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PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu17214 NM_001040633 Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant c, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu17239 NM_024429 Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant b, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu18355 NM_016203 Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu41594 XM_005250002 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu41595 XM_005250003 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu41596 XM_006716021 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X9, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu41597 XM_005250004 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu41598 XM_005250005 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu41599 XM_005250006 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu41600 XM_005250007 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X6, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu41601 XM_005250009 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X8, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu17214C NM_001040633 Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant c, mRNA. Customized vector On-demand 7-9 $269.00
OHu17239C NM_024429 Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant b, mRNA. Customized vector In-stock 5-7 $149.00
OHu18355C NM_016203 Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant a, mRNA. Customized vector On-demand 7-9 $269.00
OHu41594C XM_005250002 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X1, mRNA. Customized vector On-demand 7-9 $269.00
OHu41595C XM_005250003 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X2, mRNA. Customized vector On-demand 7-9 $269.00
OHu41596C XM_006716021 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X9, mRNA. Customized vector On-demand 7-9 $269.00
OHu41597C XM_005250004 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X3, mRNA. Customized vector On-demand 7-9 $269.00
OHu41598C XM_005250005 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X4, mRNA. Customized vector On-demand 7-9 $269.00
OHu41599C XM_005250006 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X5, mRNA. Customized vector On-demand 7-9 $269.00
OHu41600C XM_005250007 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X6, mRNA. Customized vector On-demand 7-9 $269.00
OHu41601C XM_005250009 PREDICTED: Homo sapiens protein kinase, AMP-activated, gamma 2 non-catalytic subunit (PRKAG2), transcript variant X8, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol PRKAG2
Entrez Gene ID 51422
Full Name protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Synonyms AAKG, AAKG2, CMH6, H91620p, WPWS
General protein information
Preferred Names
5'-AMP-activated protein kinase subunit gamma-2
Names
5'-AMP-activated protein kinase subunit gamma-2
AMPK subunit gamma-2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7q36.1

Summary AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602743

Wolff-Parkinson-White syndrome, 194200 (3); Cardiomyopathy,

mRNA Protein Product Sequence Price Select
NM_001040633, 100913191 NP_001035723, 100913192 5'-AMP-activated protein kinase subunit gamma-2 isoform c ORF Sequence $550.00
NM_016203, 100913190 NP_057287, 33186925 5'-AMP-activated protein kinase subunit gamma-2 isoform a ORF Sequence $700.00
NM_024429, 100913188 NP_077747, 100913189 5'-AMP-activated protein kinase subunit gamma-2 isoform b ORF Sequence $269.00
XM_005250002, 530387013 XP_005250059, 530387014 5'-AMP-activated protein kinase subunit gamma-2 isoform X1 ORF Sequence $700.00
XM_005250003, 530387015 XP_005250060, 530387016 5'-AMP-activated protein kinase subunit gamma-2 isoform X2 ORF Sequence $700.00
XM_005250004, 530387017 XP_005250061, 530387018 5'-AMP-activated protein kinase subunit gamma-2 isoform X3 ORF Sequence $700.00
XM_005250005, 530387019 XP_005250062, 530387020 5'-AMP-activated protein kinase subunit gamma-2 isoform X4 ORF Sequence $700.00
XM_005250006, 578814334 XP_005250063, 530387022 5'-AMP-activated protein kinase subunit gamma-2 isoform X5 ORF Sequence $550.00
XM_005250007, 578814335 XP_005250064, 530387024 5'-AMP-activated protein kinase subunit gamma-2 isoform X6 ORF Sequence $550.00
XM_005250009, 530387027 XP_005250066, 530387028 5'-AMP-activated protein kinase subunit gamma-2 isoform X8 ORF Sequence $400.00
XM_006716021, 578814332 XP_006716084, 578814333 5'-AMP-activated protein kinase subunit gamma-2 isoform X9 ORF Sequence $700.00
KEGG
hsa04910Insulin signaling pathway
hsa04920Adipocytokine signaling pathway
hsa04710Circadian rhythm
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa04932Non-alcoholic fatty liver disease (NAFLD)
hsa04921Oxytocin signaling pathway
hsa04068FoxO signaling pathway
hsa04152AMPK signaling pathway
WikiPathways
WP1471TOR signaling
WP1403AMPK signaling
WP1541Energy Metabolism
Reactome
REACT_11082Import of palmitoyl-CoA into the mitochondrial matrix
REACT_1988AMPK inhibits chREBP transcriptional activation activity
REACT_11123Membrane Trafficking
REACT_1505Integration of energy metabolism
REACT_976PI3K Cascade
REACT_762IRS-related events
REACT_1195Insulin receptor signalling cascade
REACT_498Signaling by Insulin receptor
REACT_332IRS-mediated signalling
REACT_456PKB-mediated events
REACT_6838mTOR signalling
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_21387Energy dependent regulation of mTOR by LKB1-AMPK
REACT_21393Regulation of Rheb GTPase activity by AMPK
REACT_21285Regulation of AMPK activity via LKB1
REACT_111217Metabolism
REACT_111102Signal Transduction
REACT_147867Translocation of GLUT4 to the plasma membrane
REACT_150359Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
REACT_150203IRS-related events triggered by IGF1R
REACT_150210IGF1R signaling cascade
REACT_200751Organelle biogenesis and maintenance
REACT_200686Activation of PPARGC1A (PGC-1alpha) by phosphorylation
REACT_200788Mitochondrial biogenesis
Homo sapiens (human)PRKAG2NP_057287.2
Pan troglodytes (chimpanzee)PRKAG2XP_003318972.1
Canis lupus familiaris (dog)PRKAG2XP_532769.3
Bos taurus (cattle)PRKAG2XP_002687025.2
Mus musculus (house mouse)Prkag2NP_663376.2
Rattus norvegicus (Norway rat)Prkag2NP_908940.1
Gallus gallus (chicken)PRKAG2NP_001265071.1
Danio rerio (zebrafish)prkag2bXP_696730.4
Xenopus (Silurana) tropicalis (western clawed frog)prkag1NP_001121411.1
Process
IDNameEvidence
GO:0005977glycogen metabolic processIMP
GO:0006110regulation of glycolytic processIMP
GO:0006112energy reserve metabolic processTAS
GO:0006469negative regulation of protein kinase activityIDA
GO:0006633fatty acid biosynthetic processIEA
GO:0006754ATP biosynthetic processTAS
GO:0006853carnitine shuttleTAS
GO:0007050cell cycle arrestTAS
GO:0008286insulin receptor signaling pathwayTAS
GO:0010800positive regulation of peptidyl-threonine phosphorylationIMP
GO:0016126sterol biosynthetic processTAS
GO:0019217regulation of fatty acid metabolic processIMP
GO:0035556intracellular signal transductionIMP
GO:0042304regulation of fatty acid biosynthetic processTAS
GO:0044255cellular lipid metabolic processTAS
GO:0044281small molecule metabolic processTAS
GO:0045860positive regulation of protein kinase activityIMP
GO:0046320regulation of fatty acid oxidationTAS
GO:0046324regulation of glucose importTAS
GO:0061024membrane organizationTAS
GO:0071901negative regulation of protein serine/threonine kinase activityIDA
Component
IDNameEvidence
GO:0005615extracellular spaceIDA
GO:0005654nucleoplasmTAS
GO:0005829cytosolTAS
GO:0031588AMP-activated protein kinase complexIDA
Function
IDNameEvidence
GO:0004862cAMP-dependent protein kinase inhibitor activityIDA
GO:0005524ATP bindingIDA
GO:0008603cAMP-dependent protein kinase regulator activityIMP
GO:0008607phosphorylase kinase regulator activityIMP
GO:0016208AMP bindingIEA
GO:0019901protein kinase bindingIDA
GO:0030295protein kinase activator activityIMP
GO:0043531ADP bindingIDA
GeneCards PRKAG2
UniProt G8JLM0, Q9UGJ0
Vega OTTHUMG00000157324
MIM 602743
Ensembl ENSG00000106617
HGNC 9386
HPRD 04119

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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