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PRRX2 paired related homeobox 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_016307 Homo sapiens paired related homeobox 2 (PRRX2), mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_006717142 PREDICTED: Homo sapiens paired related homeobox 2 (PRRX2), transcript variant X1, partial mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Related Services

Gene Symbol PRRX2
Entrez Gene ID 51450
Full Name paired related homeobox 2
Synonyms PMX2, PRX2
General protein information
Preferred Names
paired mesoderm homeobox protein 2
Names
paired mesoderm homeobox protein 2
PRX-2
paired-related homeobox protein 2
paired-like homeodomain protein PRX2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q34.1

Summary The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008].
Disorder

MIM: 604675

mRNA Protein Product Sequence Price Select
NM_016307, 38505203 NP_057391, 7706659 paired mesoderm homeobox protein 2 ORF Sequence $300.00
XM_006717142, 578817550 XP_006717205, 578817551 paired mesoderm homeobox protein 2 isoform X1 ORF Sequence $150.00
Homo sapiens (human)PRRX2NP_057391.1
Pan troglodytes (chimpanzee)PRRX2XP_520310.2
Macaca mulatta (Rhesus monkey)PRRX2XP_001107634.1
Canis lupus familiaris (dog)PRRX2XP_548419.3
Bos taurus (cattle)PRRX2XP_002691720.3
Mus musculus (house mouse)Prrx2NP_033142.2
Rattus norvegicus (Norway rat)Prrx2NP_001099209.1
Gallus gallus (chicken)PRRX2XP_415476.3
Xenopus (Silurana) tropicalis (western clawed frog)prrx2XP_002940803.1
Process
IDNameEvidence
GO:0002053positive regulation of mesenchymal cell proliferationIEA
GO:0006355regulation of transcription, DNA-templatedNAS
GO:0030326embryonic limb morphogenesisIEA
GO:0042472inner ear morphogenesisIEA
GO:0042474middle ear morphogenesisIEA
GO:0045880positive regulation of smoothened signaling pathwayIEA
GO:0048701embryonic cranial skeleton morphogenesisIEA
GO:0048844artery morphogenesisIEA
GO:0051216cartilage developmentIEA
Component
IDNameEvidence
GO:0005634nucleusIEA
Function
IDNameEvidence
GO:0003700sequence-specific DNA binding transcription factor activityNAS
GO:0043565sequence-specific DNA bindingIEA
GeneCards PRRX2
UniProt Q99811
Vega OTTHUMG00000020790
MIM 604675
Ensembl ENSG00000167157
HGNC 21338
HPRD 05244

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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