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Sequence in raw or FASTA format:

Database:

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PDPK1 3-phosphoinositide dependent protein kinase-1 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001261816 Homo sapiens 3-phosphoinositide dependent protein kinase-1 (PDPK1), transcript variant 3, mRNA. ORF Sequence $395.85
Peptide Services
Antibody Services
Protein Services
NM_002613 Homo sapiens 3-phosphoinositide dependent protein kinase-1 (PDPK1), transcript variant 1, mRNA. ORF Sequence $484.59
Peptide Services
Antibody Services
Protein Services
NM_031268 Homo sapiens 3-phosphoinositide dependent protein kinase-1 (PDPK1), transcript variant 2, mRNA. ORF Sequence $374.10
Peptide Services
Antibody Services
Protein Services


Gene Symbol PDPK1
Entrez Gene ID 5170
Full Name 3-phosphoinositide dependent protein kinase-1
Synonyms MGC20087, MGC35290, PDK1, PRO0461
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p13.3

Summary
Disorder

MIM: 605213

mRNA Protein Product Sequence Price Select
NM_001261816, 387849238 NP_001248745, 387849239 3-phosphoinositide-dependent protein kinase 1 isoform 3 Full Length $3164.40
ORF Sequence $395.85
NM_002613, 387849236 NP_002604, 4505695 3-phosphoinositide-dependent protein kinase 1 isoform 1 Full Length $3259.35
ORF Sequence $484.59
NM_031268, 387849237 NP_112558, 47680169 3-phosphoinositide-dependent protein kinase 1 isoform 2 Full Length $3087.90
ORF Sequence $374.10
KEGG
hsa05223Non-small cell lung cancer
hsa03320PPAR signaling pathway
hsa05215Prostate cancer
hsa04150mTOR signaling pathway
hsa05213Endometrial cancer
hsa04510Focal adhesion
hsa04910Insulin signaling pathway
hsa04151PI3K-Akt signaling pathway
hsa04960Aldosterone-regulated sodium reabsorption
WikiPathways
WP2261Signaling Pathways in Glioblastoma
WP306Focal Adhesion
WP185Integrin-mediated cell adhesion
WP1544MicroRNAs in cardiomyocyte hypertrophy
WP2332Interleukin-11 Signaling Pathway
WP23B Cell Receptor Signaling Pathway
WP481Insulin Signaling
WP2032TSH signaling pathway
WP69TCR Signaling Pathway
Pathway Interaction Database
pi3kcipathwayClass I PI3K signaling events
pi3kplctrkpathwayTrk receptor signaling mediated by PI3K and PLC-gamma
vegfr1_pathwayVEGFR1 specific signals
pi3kciaktpathwayClass I PI3K signaling events mediated by Akt
mtor_4pathwaymTOR signaling pathway
bcr_5pathwayBCR signaling pathway
cxcr4_pathwayCXCR4-mediated signaling events
tgfbrpathwayTGF-beta receptor signaling
faspathwayFAS (CD95) signaling pathway
insulin_pathwayInsulin Pathway
kitpathwaySignaling events mediated by Stem cell factor receptor (c-Kit)
cxcr3pathwayCXCR3-mediated signaling events
igf1_pathwayIGF1 pathway
vegfr1_2_pathwaySignaling events mediated by VEGFR1 and VEGFR2
fgf_pathwayFGF signaling pathway
cd8tcrpathwayTCR signaling in naive CD8+ T cells
tcr_pathwayTCR signaling in naive CD4+ T cells
erbb1_downstream_pathwayErbB1 downstream signaling
met_pathwaySignaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
Reactome
REACT_14797Signaling by GPCR
REACT_147814DAP12 signaling
REACT_1695GPVI-mediated activation cascade
REACT_75829PIP3 activates AKT signaling
REACT_20563Activation of NMDA receptor upon glutamate binding and postsynaptic events
REACT_75774Adaptive Immune System
REACT_147727Constitutive PI3K/AKT Signaling in Cancer
REACT_111040Signaling by SCF-KIT
REACT_11061Signalling by NGF
REACT_15523Integrin alphaIIb beta3 signaling
REACT_20510RSK activation
REACT_115871Signaling by EGFR in Cancer
REACT_13685Neuronal System
REACT_19344Costimulation by the CD28 family
REACT_12555Downstream TCR signaling
REACT_116008PI3K events in ERBB2 signaling
REACT_21272Downstream signaling of activated FGFR
REACT_115961PI3K events in ERBB4 signaling
REACT_976PI3K Cascade
REACT_762IRS-related events
REACT_111102Signal Transduction
REACT_12578GAB1 signalosome
REACT_12464PI3K/AKT activation
REACT_1195Insulin receptor signalling cascade
REACT_19358CD28 dependent PI3K/Akt signaling
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_120736Signaling by FGFR in disease
REACT_147723PI3K/AKT Signaling in Cancer
REACT_13477Transmission across Chemical Synapses
REACT_115755Signaling by ERBB2
REACT_12526TCR signaling
REACT_16888Signaling by PDGF
REACT_19290G beta:gamma signalling through PI3Kgamma
REACT_6900Immune System
REACT_790Activation of PKB
REACT_147694DAP12 interactions
REACT_20568CREB phosphorylation through the activation of Ras
REACT_115596Signaling by ERBB4
REACT_9470Signaling by FGFR
REACT_19405CTLA4 inhibitory signaling
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_798Platelet activation, signaling and aggregation
REACT_21270PI-3K cascade
REACT_116125Disease
REACT_17025Downstream signal transduction
REACT_9417Signaling by EGFR
REACT_6802Innate Immune System
REACT_20593Post NMDA receptor activation events
REACT_118638Downstream Signaling Events Of B Cell Receptor (BCR)
REACT_604Hemostasis
REACT_19388G-protein beta:gamma signalling
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_332IRS-mediated signalling
REACT_498Signaling by Insulin receptor
REACT_13552Integrin cell surface interactions
REACT_278Platelet Aggregation (Plug Formation)
REACT_19184GPCR downstream signaling
REACT_19183CD28 co-stimulation
Homo sapiens (human)PDPK1NP_002604.1
Canis lupus familiaris (dog)PDPK1XP_537000.2
Bos taurus (cattle)PDPK1XP_002697908.1
Mus musculus (house mouse)Pdpk1NP_035192.2
Rattus norvegicus (Norway rat)Pdpk1NP_112343.1
Gallus gallus (chicken)PDPK1NP_001012547.1
Danio rerio (zebrafish)pdpk1bNP_991262.1
Drosophila melanogaster (fruit fly)Pdk1NP_728472.1
Caenorhabditis eleganspdk-1NP_001024742.1
Arabidopsis thaliana (thale cress)PDK1NP_568138.1
Arabidopsis thaliana (thale cress)AT3G10540NP_187665.2

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
3-phosphoinositide-dependent protein kinase 1
Names
3-phosphoinositide-dependent protein kinase 1
PkB-like 1
PkB kinase like gene 1
NP_001248745.1
NP_002604.1
NP_112558.2

Interactant

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