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PEPD peptidase D [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu24752 NM_001166056 Homo sapiens peptidase D (PEPD), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu24790 NM_000285 Homo sapiens peptidase D (PEPD), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu25079 NM_001166057 Homo sapiens peptidase D (PEPD), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu24752C NM_001166056 Homo sapiens peptidase D (PEPD), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00
OHu24790C NM_000285 Homo sapiens peptidase D (PEPD), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00
OHu25079C NM_001166057 Homo sapiens peptidase D (PEPD), transcript variant 3, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol PEPD
Entrez Gene ID 5184
Full Name peptidase D
Synonyms PROLIDASE
General protein information
Preferred Names
xaa-Pro dipeptidase
Names
xaa-Pro dipeptidase
imidodipeptidase
X-Pro dipeptidase
proline dipeptidase
aminoacyl-L-proline hydrolase
NP_000276.2
NP_001159528.1
NP_001159529.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.11

Summary This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
Disorder

MIM: 613230

Prolidase deficiency, 170100 (3)

mRNA Protein Product Sequence Price Select
NM_000285, 260593661 NP_000276, 149589008 xaa-Pro dipeptidase isoform 1 ORF Sequence $360.00
NM_001166056, 260593662 NP_001159528, 260593663 xaa-Pro dipeptidase isoform 2 ORF Sequence $550.00
NM_001166057, 260593664 NP_001159529, 260593665 xaa-Pro dipeptidase isoform 3 ORF Sequence $550.00
Homo sapiens (human)PEPDNP_000276.2
Pan troglodytes (chimpanzee)PEPDXP_512574.3
Macaca mulatta (Rhesus monkey)PEPDXP_001108725.2
Canis lupus familiaris (dog)PEPDXP_533702.2
Bos taurus (cattle)PEPDNP_001073787.2
Mus musculus (house mouse)PepdNP_032846.2
Rattus norvegicus (Norway rat)PepdNP_001009641.1
Gallus gallus (chicken)PEPDNP_001073185.1
Danio rerio (zebrafish)pepdNP_944594.1
Drosophila melanogaster (fruit fly)Dip-CNP_650192.1
Caenorhabditis elegansK12C11.1NP_490843.1
Arabidopsis thaliana (thale cress)AT4G29490NP_194678.2
Xenopus (Silurana) tropicalis (western clawed frog)pepdNP_001008094.1
Process
IDNameEvidence
GO:0006508proteolysisIEA
GO:0006520cellular amino acid metabolic processTAS
GO:0030574collagen catabolic processIEA
Component
IDNameEvidence
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0004177aminopeptidase activityIEA
GO:0004181metallocarboxypeptidase activityTAS
GO:0016805dipeptidase activityIEA
GO:0030145manganese ion bindingIEA
GeneCards PEPD
UniProt P12955
Vega OTTHUMG00000180470
MIM 613230
Ensembl ENSG00000124299
HGNC 8840
HPRD 01358

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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