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Sequence in raw or FASTA format:


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PF4 platelet factor 4 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_002619 Homo sapiens platelet factor 4 (PF4), mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10

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Gene Symbol PF4
Entrez Gene ID 5196
Full Name platelet factor 4
Synonyms CXCL4, MGC138298, SCYB4
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. [provided by RefSeq, Mar 2012].

MIM: 173460

mRNA Protein Product Sequence Price Select
NM_002619, 380254445 NP_002610, 4505733 platelet factor 4 precursor ORF Sequence $99.00
hsa04062Chemokine signaling pathway
hsa04060Cytokine-cytokine receptor interaction
Pathway Interaction Database
cxcr3pathwayCXCR3-mediated signaling events
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_12051Cell surface interactions at the vascular wall
REACT_111102Signal Transduction
REACT_14797Signaling by GPCR
REACT_318Platelet degranulation
REACT_19231G alpha (i) signalling events
REACT_15344Chemokine receptors bind chemokines
REACT_21340GPCR ligand binding
REACT_2051Formation of Fibrin Clot (Clotting Cascade)
REACT_19184GPCR downstream signaling
REACT_798Platelet activation, signaling and aggregation
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_14819Peptide ligand-binding receptors
REACT_1439Common Pathway
Homo sapiens (human)PF4NP_002610.1
Pan troglodytes (chimpanzee)PF4XP_001155980.1
Macaca mulatta (Rhesus monkey)PF4XP_001102788.1
Bos taurus (cattle)PF4NP_001094532.1
Mus musculus (house mouse)Pf4NP_064316.1
Rattus norvegicus (Norway rat)Pf4NP_001007730.1
GeneCards PF4
PDB 1PFN, 1F9S, 1DN3, 1PFM, 1RHP, 1F9Q, 1F9R
UniProt P02776
MIM 173460
Ensembl ENSG00000163737
HGNC 8861
HPRD 01426

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
platelet factor 4
platelet factor 4
C-X-C motif chemokine 4
chemokine (C-X-C motif) ligand 4


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