• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


PFKM phosphofructokinase, muscle [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000289 Homo sapiens phosphofructokinase, muscle (PFKM), transcript variant 4, mRNA. GenEZ ORF Cloning In-stock $809.00 $760.00 15
NM_001166686 Homo sapiens phosphofructokinase, muscle (PFKM), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $899.00 20
NM_001166687 Homo sapiens phosphofructokinase, muscle (PFKM), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $809.00 $760.00 15
NM_001166688 Homo sapiens phosphofructokinase, muscle (PFKM), transcript variant 3, mRNA. GenEZ ORF Cloning In-stock $809.00 $760.00 15

*Business Day

Related Services

Gene Symbol PFKM
Entrez Gene ID 5213
Full Name phosphofructokinase, muscle
Synonyms GSD7, MGC8699, PFK-1, PFK1, PFKA, PFKX
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13.3

Summary Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009].
Disorder

MIM: 610681

Glycogen storage disease VII, 232800 (3)

mRNA Protein Product Sequence Price Select
NM_000289, 266453668 NP_000280, 4505749 6-phosphofructokinase, muscle type isoform 2 ORF Sequence $660.00
NM_001166686, 266453618 NP_001160158, 266453619 6-phosphofructokinase, muscle type isoform 1 ORF Sequence $750.00
NM_001166687, 266453747 NP_001160159, 266453748 6-phosphofructokinase, muscle type isoform 2 ORF Sequence $660.00
NM_001166688, 266453767 NP_001160160, 266453768 6-phosphofructokinase, muscle type isoform 2 ORF Sequence $660.00
KEGG
hsa00010Glycolysis / Gluconeogenesis
hsa_M00001Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
hsa00030Pentose phosphate pathway
hsa00051Fructose and mannose metabolism
hsa00052Galactose metabolism
Pathway Interaction Database
myc_activpathwayValidated targets of C-MYC transcriptional activation
WikiPathways
WP534Glycolysis and Gluconeogenesis
WP481Insulin Signaling
BIOCYC
HUMAN_GLYCOLYSISglycolysis I
Reactome
REACT_723Glucose metabolism
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_1383Glycolysis
Homo sapiens (human)PFKMNP_001160158.1
Pan troglodytes (chimpanzee)PFKMXP_509029.2
Macaca mulatta (Rhesus monkey)PFKMXP_002798592.1
Canis lupus familiaris (dog)PFKMNP_001003199.1
Bos taurus (cattle)PFKMNP_001068736.1
Mus musculus (house mouse)PfkmNP_067489.3
Rattus norvegicus (Norway rat)PfkmNP_113903.1
Gallus gallus (chicken)PFKMNP_989554.2
Danio rerio (zebrafish)pfkmbNP_001082886.1
Danio rerio (zebrafish)pfkmaNP_001004575.1
Drosophila melanogaster (fruit fly)PfkNP_724891.2
Caenorhabditis elegansY71H10A.1NP_741738.1
GeneCards PFKM
UniProt P08237
MIM 610681
Ensembl ENSG00000152556
HGNC 8877
HPRD 01988

Related articles in PubMed

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
6-phosphofructokinase, muscle type
Names
6-phosphofructokinase, muscle type
PFK-A
phosphohexokinase
phosphofructokinase 1
phosphofructokinase-M
6-phosphofructo-1-kinase
phosphofructo-1-kinase isozyme A
phosphofructokinase, polypeptide X
NP_000280.1
NP_001160158.1
NP_001160159.1
NP_001160160.1

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.