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Sequence in raw or FASTA format:

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PGK1 phosphoglycerate kinase 1 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000291 Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA. ORF Sequence $363.66
Peptide Services
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Gene Symbol PGK1
Entrez Gene ID 5230
Full Name phosphoglycerate kinase 1
Synonyms MGC117307, MGC142128, MGC8947, MIG10, PGKA
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq13

Summary The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. This gene lies on the X-chromosome, while a related pseudogene also has been found on the X-chromosome and another on chromosome 19. [provided by RefSeq, Oct 2008].
Disorder

MIM: 311800

Phosphoglycerate kinase 1 deficiency, 300653 (3)

mRNA Protein Product Sequence Price Select
NM_000291, 183603937 NP_000282, 4505763 phosphoglycerate kinase 1 Full Length $707.31
ORF Sequence $363.66
KEGG
hsa04066HIF-1 signaling pathway
hsa00010Glycolysis / Gluconeogenesis
hsa_M00002Glycolysis, core module involving three-carbon compounds
hsa_M00003Gluconeogenesis, oxaloacetate => fructose-6P
hsa_M00001Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
WikiPathways
WP534Glycolysis and Gluconeogenesis
Pathway Interaction Database
hif2pathwayHIF-2-alpha transcription factor network
hif1_tfpathwayHIF-1-alpha transcription factor network
BIOCYC
HUMAN_GLYCOLYSISglycolysis I
HUMAN_GLUCONEO-PWYgluconeogenesis I
Reactome
REACT_111217Metabolism
REACT_1520Gluconeogenesis
REACT_1383Glycolysis
REACT_474Metabolism of carbohydrates
REACT_723Glucose metabolism
Homo sapiens (human)PGK1NP_000282.1
Pan troglodytes (chimpanzee)PGK1NP_001129210.1
Macaca mulatta (Rhesus monkey)PGK1XP_001100787.1
Canis lupus familiaris (dog)PGK1XP_849992.1
Bos taurus (cattle)PGK1NP_001029471.1
Mus musculus (house mouse)Pgk1NP_032854.2
Rattus norvegicus (Norway rat)Pgk1NP_445743.2
Gallus gallus (chicken)PGK1NP_990316.1
Danio rerio (zebrafish)pgk1NP_998552.1
Drosophila melanogaster (fruit fly)PgkNP_476676.1
Caenorhabditis eleganspgk-1NP_491245.1
GeneCards PGK1
PDB 2Y3I, 2XE6, 2WZC, 2WZD, 3C3C, 2ZGV, 2X13, 2XE8, 3C3B, 2XE7, 2WZB, 2X15, 2X14, 3C39, 2YBE, 3C3A
UniProt P00558
MIM 311800
Ensembl ENSG00000102144
HGNC 8896
HPRD 02412

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
phosphoglycerate kinase 1
Names
phosphoglycerate kinase 1
PRP 2
primer recognition protein 2
cell migration-inducing gene 10 protein
NP_000282.1

Interactant

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