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PKD2 polycystic kidney disease 2 (autosomal dominant) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000297 Homo sapiens polycystic kidney disease 2 (autosomal dominant) (PKD2), mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Gene Symbol PKD2
Entrez Gene ID 5311
Full Name polycystic kidney disease 2 (autosomal dominant)
Synonyms APKD2, MGC138466, MGC138468, PC2, PKD4, Pc-2, TRPP2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q22.1

Summary This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011].
Disorder

MIM: 173910

Polycystic kidney disease 2, 613095 (3)

mRNA Protein Product Sequence Price Select
NM_000297, 325121002 NP_000288, 4505835 polycystin-2 ORF Sequence $750.00
Homo sapiens (human)PKD2NP_000288.1
Pan troglodytes (chimpanzee)PKD2XP_003310458.1
Macaca mulatta (Rhesus monkey)PKD2XP_001099242.1
Canis lupus familiaris (dog)PKD2XP_544974.2
Bos taurus (cattle)PKD2NP_001039777.1
Mus musculus (house mouse)Pkd2NP_032887.3
Rattus norvegicus (Norway rat)Pkd2XP_573552.3
Gallus gallus (chicken)PKD2NP_001026311.1
Danio rerio (zebrafish)pkd2NP_001002310.1
Caenorhabditis eleganspkd-2NP_502838.3
GeneCards PKD2
PDB 2Y4Q, 2KQ6, 2KLE, 2KLD, 3HRO, 3HRN
UniProt Q13563, Q9UEU6
MIM 173910
Ensembl ENSG00000118762
HGNC 9009
HPRD 01437

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Interactant



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