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PLCB4 phospholipase C, beta 4 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000933 Homo sapiens phospholipase C, beta 4 (PLCB4), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001172646 Homo sapiens phospholipase C, beta 4 (PLCB4), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_182797 Homo sapiens phospholipase C, beta 4 (PLCB4), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25

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Gene Symbol PLCB4
Entrez Gene ID 5332
Full Name phospholipase C, beta 4
Synonyms FLJ16169, PI-PLC
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

20

20p12

Summary The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010].
Disorder

MIM: 600810

mRNA Protein Product Sequence Price Select
NM_000933, 289547588 NP_000924, 289547589 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform a ORF Sequence $1500.00
NM_001172646, 289547593 NP_001166117, 289547594 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform c ORF Sequence $1500.00
NM_182797, 289547590 NP_877949, 289547591 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform b ORF Sequence $1500.00
KEGG
hsa04916Melanogenesis
hsa_M00130Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
hsa04270Vascular smooth muscle contraction
hsa05146Amoebiasis
hsa00562Inositol phosphate metabolism
hsa04725Cholinergic synapse
hsa05143African trypanosomiasis
hsa04310Wnt signaling pathway
hsa04724Glutamatergic synapse
hsa04961Endocrine and other factor-regulated calcium reabsorption
hsa04020Calcium signaling pathway
hsa04713Circadian entrainment
hsa04912GnRH signaling pathway
hsa04972Pancreatic secretion
hsa04730Long-term depression
hsa04728Dopaminergic synapse
hsa04720Long-term potentiation
hsa05016Huntington's disease
hsa04070Phosphatidylinositol signaling system
hsa04062Chemokine signaling pathway
hsa04970Salivary secretion
hsa04540Gap junction
hsa04723Retrograde endocannabinoid signaling
hsa04971Gastric acid secretion
hsa05142Chagas disease (American trypanosomiasis)
hsa04726Serotonergic synapse
hsa05010Alzheimer's disease
WikiPathways
WP2059Alzheimers Disease
Reactome
REACT_15295Opioid Signalling
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_19184GPCR downstream signaling
REACT_15426PLC beta mediated events
REACT_15526G-protein mediated events
REACT_18283G alpha (q) signalling events
Homo sapiens (human)PLCB4NP_001166117.1
Pan troglodytes (chimpanzee)PLCB4XP_001168348.2
Macaca mulatta (Rhesus monkey)PLCB4XP_002798260.1
Canis lupus familiaris (dog)PLCB4XP_534349.3
Bos taurus (cattle)PLCB4NP_001159982.1
Mus musculus (house mouse)Plcb4NP_038857.1
Rattus norvegicus (Norway rat)Plcb4NP_077329.1
Gallus gallus (chicken)PLCB4NP_001186364.1
Danio rerio (zebrafish)LOC100537538XP_003200348.1
Drosophila melanogaster (fruit fly)norpANP_001014720.1
Caenorhabditis elegansegl-8NP_001021346.1
GeneCards PLCB4
UniProt E2QRH8, Q15147
MIM 600810
Ensembl ENSG00000101333
HGNC 9059
HPRD 02885

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Interactant



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