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POU3F2 POU class 3 homeobox 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_005604 Homo sapiens POU class 3 homeobox 2 (POU3F2), mRNA. GenEZ ORF Cloning On-demand TBD TBD

*Business Day

Related Services

Gene Symbol POU3F2
Entrez Gene ID 5454
Full Name POU class 3 homeobox 2
Synonyms BRN2, N-Oct3, OCT7, OTF-7, OTF7, POUF3, brn-2, oct-7
General protein information
Preferred Names
POU domain, class 3, transcription factor 2
Names
POU domain, class 3, transcription factor 2
brain-2
octamer-binding protein 7
octamer-binding transcription factor 7
brain-specific homeobox/POU domain protein 2
nervous system-specific octamer-binding transcription factor N-Oct-3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6q16

Summary This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells. [provided by RefSeq, Mar 2012].
Disorder

MIM: 600494

mRNA Protein Product Sequence Price Select
NM_005604, 380254475 NP_005595, 51702521 POU domain, class 3, transcription factor 2 ORF Sequence $550.00
WikiPathways
WP706SIDS Susceptibility Pathways
Homo sapiens (human)POU3F2NP_005595.2
Pan troglodytes (chimpanzee)POU3F2XP_003950948.1
Macaca mulatta (Rhesus monkey)LOC694524XP_001083202.1
Canis lupus familiaris (dog)LOC481931XP_539052.3
Bos taurus (cattle)POU3F2NP_001073817.1
Mus musculus (house mouse)Pou3f2NP_032925.1
Rattus norvegicus (Norway rat)Pou3f2NP_742082.1
Danio rerio (zebrafish)pou3f2bNP_571235.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100486226NP_001263306.1
Process
IDNameEvidence
GO:0006351transcription, DNA-templatedIEA
GO:0008284positive regulation of cell proliferationIDA
GO:0008544epidermis developmentIEA
GO:0014002astrocyte developmentIEA
GO:0021799cerebral cortex radially oriented cell migrationIEA
GO:0021869forebrain ventricular zone progenitor cell divisionIEA
GO:0021979hypothalamus cell differentiationIEA
GO:0021985neurohypophysis developmentIEA
GO:0022011myelination in peripheral nervous systemIEA
GO:0030182neuron differentiationIEA
GO:0040018positive regulation of multicellular organism growthIEA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0050770regulation of axonogenesisIEA
GO:0071310cellular response to organic substanceIEA
Component
IDNameEvidence
GO:0005634nucleusIEA
GO:0005667transcription factor complexIEA
Function
IDNameEvidence
GO:0001105RNA polymerase II transcription coactivator activityIEA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0005515protein bindingIPI
GO:0042802identical protein bindingIPI
GO:0043565sequence-specific DNA bindingIEA
GeneCards POU3F2
UniProt P20265
Vega OTTHUMG00000015258
MIM 600494
Ensembl ENSG00000184486
HGNC 9215
HPRD 02734

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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