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POU3F4 POU class 3 homeobox 4 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu20520 NM_000307 Homo sapiens POU class 3 homeobox 4 (POU3F4), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu20520C NM_000307 Homo sapiens POU class 3 homeobox 4 (POU3F4), mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol POU3F4
Entrez Gene ID 5456
Full Name POU class 3 homeobox 4
Synonyms BRAIN-4, BRN-4, BRN4, DFN3, DFNX2, OCT-9, OTF-9, OTF9
General protein information
Preferred Names
POU domain, class 3, transcription factor 4
Names
POU domain, class 3, transcription factor 4
octamer-binding transcription factor 9
brain-specific homeobox/POU domain protein 4
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq21.1

Summary This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness. [provided by RefSeq, Dec 2012].
Disorder

MIM: 300039

Deafness, X-linked 2, 304400 (3)

mRNA Protein Product Sequence Price Select
NM_000307, 433288479 NP_000298, 433288480 POU domain, class 3, transcription factor 4 ORF Sequence $400.00
Homo sapiens (human)POU3F4NP_000298.3
Pan troglodytes (chimpanzee)POU3F4XP_003317585.1
Macaca mulatta (Rhesus monkey)POU3F4XP_001104059.1
Canis lupus familiaris (dog)POU3F4XP_549108.1
Bos taurus (cattle)POU3F4XP_002699986.1
Mus musculus (house mouse)Pou3f4NP_032927.1
Rattus norvegicus (Norway rat)Pou3f4NP_058948.1
Xenopus (Silurana) tropicalis (western clawed frog)pou3f4NP_001090728.1
Process
IDNameEvidence
GO:0006355regulation of transcription, DNA-templatedIEA
GO:0006366transcription from RNA polymerase II promoterIEA
GO:0007605sensory perception of soundIEA
GO:0021879forebrain neuron differentiationIEA
GO:0090103cochlea morphogenesisISS
GO:2001054negative regulation of mesenchymal cell apoptotic processISS
Component
IDNameEvidence
GO:0005634nucleusIEA
Function
IDNameEvidence
GO:0003680AT DNA bindingIEA
GO:0003690double-stranded DNA bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GeneCards POU3F4
UniProt P49335
Vega OTTHUMG00000021919
MIM 300039
Ensembl ENSG00000196767
HGNC 9217
HPRD 02076

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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