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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


FEV FEV (ETS oncogene family) [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu19395 NM_017521 Homo sapiens FEV (ETS oncogene family) (FEV), mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu19395C NM_017521 Homo sapiens FEV (ETS oncogene family) (FEV), mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol FEV
Entrez Gene ID 54738
Full Name FEV (ETS oncogene family)
Synonyms HSRNAFEV, PET-1
General protein information
Preferred Names
protein FEV
Names
protein FEV
fifth Ewing variant protein
PC12 ETS domain-containing transcription factor 1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q36

Summary This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008].
Disorder

MIM: 607150

mRNA Protein Product Sequence Price Select
NM_017521, 56550101 NP_059991, 8923789 protein FEV ORF Sequence $250.00
KEGG
hsa05202Transcriptional misregulation in cancer
WikiPathways
WP706SIDS Susceptibility Pathways
Homo sapiens (human)FEVNP_059991.1
Pan troglodytes (chimpanzee)FEVXP_003309530.1
Macaca mulatta (Rhesus monkey)FEVXP_001095962.1
Bos taurus (cattle)FEVNP_001179532.1
Mus musculus (house mouse)FevNP_694751.1
Rattus norvegicus (Norway rat)FevNP_653354.2
Gallus gallus (chicken)LOC100857480XP_003641694.1
Danio rerio (zebrafish)fevNP_001074126.1
Xenopus (Silurana) tropicalis (western clawed frog)fevXP_002934005.1
Process
IDNameEvidence
GO:0006357regulation of transcription from RNA polymerase II promoterIBA
GO:0006366transcription from RNA polymerase II promoterTAS
GO:0030154cell differentiationIBA
GO:0042551neuron maturationIEA
GO:0045893positive regulation of transcription, DNA-templatedIEA
GO:0048665neuron fate specificationIEA
Component
IDNameEvidence
GO:0005634nucleusIBA
Function
IDNameEvidence
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activityIBA
GO:0003690double-stranded DNA bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityTAS
GO:0003714transcription corepressor activityTAS
GO:0043565sequence-specific DNA bindingIEA
GeneCards FEV
PDB 3ZP5, 2YPR
UniProt Q99581
Vega OTTHUMG00000133080
MIM 607150
Ensembl ENSG00000163497
HGNC 18562
HPRD 06193

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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