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CTSA cathepsin A [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000308 Homo sapiens cathepsin A (CTSA), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001127695 Homo sapiens cathepsin A (CTSA), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001167594 Homo sapiens cathepsin A (CTSA), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Gene Symbol CTSA
Entrez Gene ID 5476
Full Name cathepsin A
Synonyms GLB2, GSL, NGBE, PPCA, PPGB
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

20

20q13.1

Summary This gene encodes a glycoprotein which associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers. The formation of this complex provides a protective role for stability and activity. Deficiencies in this gene are linked to multiple forms of galactosialidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 613111

Galactosialidosis, 256540 (3)

mRNA Protein Product Sequence Price Select
NM_000308, 119395728 NP_000299, 119395729 lysosomal protective protein isoform a precursor ORF Sequence $550.00
NM_001127695, 189163484 NP_001121167, 189163485 lysosomal protective protein isoform b precursor ORF Sequence $550.00
NM_001167594, 262527234 NP_001161066, 262527235 lysosomal protective protein isoform c precursor ORF Sequence $550.00
KEGG
hsa04614Renin-angiotensin system
hsa04142Lysosome
Reactome
REACT_111217Metabolism
REACT_6900Immune System
REACT_22258Metabolism of lipids and lipoproteins
REACT_120870Phospholipid metabolism
REACT_116105Glycosphingolipid metabolism
REACT_75774Adaptive Immune System
REACT_121399MHC class II antigen presentation
REACT_19323Sphingolipid metabolism
Homo sapiens (human)CTSANP_000299.2
Pan troglodytes (chimpanzee)CTSAXP_001159669.2
Macaca mulatta (Rhesus monkey)CTSAXP_001106032.1
Canis lupus familiaris (dog)CTSANP_001103385.1
Bos taurus (cattle)CTSANP_001030403.1
Mus musculus (house mouse)CtsaNP_032932.2
Rattus norvegicus (Norway rat)CtsaNP_001011959.1
Gallus gallus (chicken)CTSANP_001026662.1
Danio rerio (zebrafish)ctsaNP_956844.1
Caenorhabditis elegansF13D12.6NP_496507.1
Caenorhabditis elegansF41C3.5NP_494846.1
Arabidopsis thaliana (thale cress)scpl20NP_193027.5
Arabidopsis thaliana (thale cress)scpl21NP_189169.1
GeneCards CTSA
PDB 4AZ3, 3BXN, 3BP4, 4AZ0, 3BP7, 1IVY
UniProt B4E324, P10619
MIM 613111
Ensembl ENSG00000064601
HGNC 9251
HPRD 02020

Related articles in PubMed

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
lysosomal protective protein
Names
lysosomal protective protein
deamidase
urinary kininase
carboxypeptidase C
carboxypeptidase L
carboxypeptidase-L
beta-galactosidase 2
lysosomal carboxypeptidase A
protective protein cathepsin A
carboxypeptidase Y-like kininase
beta-galactosidase protective protein
NP_000299.2
NP_001121167.1
NP_001161066.1

Interactant



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