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PPIB peptidylprolyl isomerase B (cyclophilin B) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000942 Homo sapiens peptidylprolyl isomerase B (cyclophilin B) (PPIB), mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10

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Gene Symbol PPIB
Entrez Gene ID 5479
Full Name peptidylprolyl isomerase B (cyclophilin B)
Synonyms CYP-S1, CYPB, MGC14109, MGC2224, OI9, SCYLP
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q21-q22

Summary The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009].
Disorder

MIM: 123841

Osteogenesis imperfecta, type IX, 259440 (3)

mRNA Protein Product Sequence Price Select
NM_000942, 44890060 NP_000933, 4758950 peptidyl-prolyl cis-trans isomerase B precursor ORF Sequence $159.00
Pathway Interaction Database
syndecan_1_pathwaySyndecan-1-mediated signaling events
WikiPathways
WP2037Prolactin Signaling Pathway
Reactome
REACT_121139Collagen biosynthesis and modifying enzymes
REACT_120729Collagen formation
REACT_118779Extracellular matrix organization
Homo sapiens (human)PPIBNP_000933.1
Pan troglodytes (chimpanzee)PPIBXP_003314755.1
Macaca mulatta (Rhesus monkey)PPIBXP_001106590.1
Canis lupus familiaris (dog)PPIBXP_852389.1
Bos taurus (cattle)PPIBNP_776577.1
Mus musculus (house mouse)PpibNP_035279.2
Rattus norvegicus (Norway rat)PpibNP_071981.1
Gallus gallus (chicken)PPIBNP_990792.1
Danio rerio (zebrafish)ppibNP_998184.1
Drosophila melanogaster (fruit fly)CG2852NP_611695.1
Caenorhabditis eleganscyn-5NP_493624.1
Caenorhabditis eleganscyn-6NP_497257.1
Arabidopsis thaliana (thale cress)AT3G55920NP_567029.1
GeneCards PPIB
PDB 3ICH, 3ICI, 1CYN
UniProt P23284
MIM 123841
Ensembl ENSG00000166794
HGNC 9255
HPRD 00458

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
peptidyl-prolyl cis-trans isomerase B
Names
peptidyl-prolyl cis-trans isomerase B
PPIase B
rotamase B
S-cyclophilin
cyclophilin-like protein
NP_000933.1

Interactant



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