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Sequence in raw or FASTA format:

Database:

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SLC30A10 solute carrier family 30, member 10 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_018713 Homo sapiens solute carrier family 30, member 10 (SLC30A10), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_006711437 PREDICTED: Homo sapiens solute carrier family 30, member 10 (SLC30A10), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $549.00 14
XM_006711438 PREDICTED: Homo sapiens solute carrier family 30, member 10 (SLC30A10), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $449.00 14
XM_006711439 PREDICTED: Homo sapiens solute carrier family 30, member 10 (SLC30A10), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $449.00 14

*Business Day

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Gene Symbol SLC30A10
Entrez Gene ID 55532
Full Name solute carrier family 30, member 10
Synonyms HMDPC, ZNT10, ZNT8, ZRC1, ZnT-10
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q41

Summary This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012].
Disorder

MIM: 611146

mRNA Protein Product Sequence Price Select
NM_018713, 52351207 NP_061183, 52351208 zinc transporter 10 ORF Sequence $550.00
XM_006711437, 578801233 XP_006711500, 578801234 zinc transporter 10 isoform X1 ORF Sequence $400.00
XM_006711438, 578801235 XP_006711501, 578801236 zinc transporter 10 isoform X2 ORF Sequence $300.00
XM_006711439, 578801237 XP_006711502, 578801238 zinc transporter 10 isoform X3 ORF Sequence $300.00
Homo sapiens (human)SLC30A10NP_061183.2
Pan troglodytes (chimpanzee)SLC30A10XP_525065.1
Macaca mulatta (Rhesus monkey)SLC30A10XP_001103570.1
Bos taurus (cattle)SLC30A10NP_001179109.1
Mus musculus (house mouse)Slc30a10NP_001028458.1
Rattus norvegicus (Norway rat)Slc30a10NP_001099455.1
Gallus gallus (chicken)SLC30A10XP_419410.3
Danio rerio (zebrafish)slc30a10NP_001121706.1
Xenopus (Silurana) tropicalis (western clawed frog)slc30a10XP_002936066.2
Process
IDNameEvidence
GO:0006829zinc ion transportIEA
GO:0055085transmembrane transportIEA
Component
IDNameEvidence
GO:0005886plasma membraneIEA
GO:0016021integral component of membraneIEA
Function
IDNameEvidence
GO:0008324cation transmembrane transporter activityIEA
GeneCards SLC30A10
UniProt B3KR19, Q6XR72
MIM 611146
HGNC 25355
HPRD 15367

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the SLC30A10 gene?

The SLC30A10 gene provides instructions for making a protein that transports the element manganese across cell membranes. Manganese is important for many cellular functions, but large amounts are toxic, particularly to brain and liver cells. The SLC30A10 protein is found in the membranes surrounding liver cells and nerve cells in the brain, as well as in the membranes of structures within these cells. The protein protects these cells from high concentrations of manganese by removing manganese when levels become elevated.

Interactant

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