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PIGV phosphatidylinositol glycan anchor biosynthesis, class V [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001202554 Homo sapiens phosphatidylinositol glycan anchor biosynthesis, class V (PIGV), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
NM_017837 Homo sapiens phosphatidylinositol glycan anchor biosynthesis, class V (PIGV), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12

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Gene Symbol PIGV
Entrez Gene ID 55650
Full Name phosphatidylinositol glycan anchor biosynthesis, class V
Synonyms FLJ20477, GPI-MT-II, PIG-V
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36.11

Summary This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia mental retardation syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011].
Disorder

MIM: 610274

mRNA Protein Product Sequence Price Select
NM_001202554, 322309864 NP_001189483, 322309865 GPI mannosyltransferase 2 ORF Sequence $360.00
NM_017837, 322309841 NP_060307, 21361771 GPI mannosyltransferase 2 ORF Sequence $360.00
KEGG
hsa00563Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
hsa_M00065GPI-anchor biosynthesis, core oligosaccharide
Reactome
REACT_952Synthesis of glycosylphosphatidylinositol (GPI)
REACT_1853Post-translational modification: synthesis of GPI-anchored proteins
REACT_22161Post-translational protein modification
REACT_17015Metabolism of proteins
Homo sapiens (human)PIGVNP_001189483.1
Macaca mulatta (Rhesus monkey)PIGVXP_001109737.1
Canis lupus familiaris (dog)PIGVXP_535346.1
Bos taurus (cattle)PIGVNP_001179434.1
Mus musculus (house mouse)PigvNP_848813.3
Rattus norvegicus (Norway rat)PigvNP_001010966.1
Gallus gallus (chicken)PIGVXP_003642609.1
Danio rerio (zebrafish)pigvNP_001186989.1
Drosophila melanogaster (fruit fly)vegNP_725630.1
Caenorhabditis elegansT09B4.1NP_491783.1
Arabidopsis thaliana (thale cress)AT1G11880NP_172652.2
GeneCards PIGV
UniProt Q9NUD9
MIM 610274
Ensembl ENSG00000060642
HGNC 26031
HPRD 07912

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
GPI mannosyltransferase 2
Names
GPI mannosyltransferase 2
Ybr004c homolog
GPI mannosyltransferase II
dol-P-Man dependent GPI mannosyltransferase

Interactant



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