• THAT   AND

Sequence in raw or FASTA format:


Blast Method:


PIGV phosphatidylinositol glycan anchor biosynthesis, class V [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001202554 Homo sapiens phosphatidylinositol glycan anchor biosynthesis, class V (PIGV), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
NM_017837 Homo sapiens phosphatidylinositol glycan anchor biosynthesis, class V (PIGV), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12

*Business Day

Related Services

Gene Symbol PIGV
Entrez Gene ID 55650
Full Name phosphatidylinositol glycan anchor biosynthesis, class V
General protein information
Preferred Names
GPI mannosyltransferase 2
GPI mannosyltransferase 2
Ybr004c homolog
GPI mannosyltransferase II
dol-P-Man dependent GPI mannosyltransferase
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia mental retardation syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011].

MIM: 610274

mRNA Protein Product Sequence Price Select
NM_001202554, 322309864 NP_001189483, 322309865 GPI mannosyltransferase 2 ORF Sequence $360.00
NM_017837, 322309841 NP_060307, 21361771 GPI mannosyltransferase 2 ORF Sequence $360.00
hsa00563Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
hsa_M00065GPI-anchor biosynthesis, core oligosaccharide
REACT_1853Post-translational modification: synthesis of GPI-anchored proteins
REACT_17015Metabolism of proteins
REACT_952Synthesis of glycosylphosphatidylinositol (GPI)
REACT_22161Post-translational protein modification
Homo sapiens (human)PIGVNP_001189483.1
Pan troglodytes (chimpanzee)PIGVXP_003949383.1
Macaca mulatta (Rhesus monkey)PIGVXP_001109737.1
Canis lupus familiaris (dog)ZDHHC18XP_005617784.1
Bos taurus (cattle)PIGVNP_001179434.1
Mus musculus (house mouse)PigvNP_848813.3
Rattus norvegicus (Norway rat)PigvNP_001010966.1
Gallus gallus (chicken)PIGVXP_003642609.1
Danio rerio (zebrafish)pigvNP_001186989.1
Drosophila melanogaster (fruit fly)vegNP_524685.2
Caenorhabditis elegansT09B4.1NP_491783.1
Arabidopsis thaliana (thale cress)AT1G11880NP_172652.2
Xenopus (Silurana) tropicalis (western clawed frog)pigvXP_002934691.1
GO:0006501C-terminal protein lipidationTAS
GO:0006506GPI anchor biosynthetic processIGI
GO:0006506GPI anchor biosynthetic processIMP
GO:0016254preassembly of GPI anchor in ER membraneTAS
GO:0043687post-translational protein modificationTAS
GO:0044267cellular protein metabolic processTAS
GO:0005789endoplasmic reticulum membraneIDA
GO:0005789endoplasmic reticulum membraneTAS
GO:0016021integral component of membraneNAS
GO:0000030mannosyltransferase activityIGI
GO:0000030mannosyltransferase activityIMP
GeneCards PIGV
UniProt Q9NUD9
Vega OTTHUMG00000004005
MIM 610274
Ensembl ENSG00000060642
HGNC 26031
HPRD 07912

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the PIGV gene?

The PIGV gene provides instructions for making an enzyme called GPI mannosyltransferase 2. This enzyme takes part in a series of steps that produce a molecule called a glycosylphosphosphatidylinositol (GPI) anchor. Specifically, GPI mannosyltransferase 2 adds the second of three molecules of a complex sugar called mannose to the GPI anchor. This step takes place in the endoplasmic reticulum, which is a structure involved in protein processing and transport within cells. The complete GPI anchor attaches (binds) to various proteins in the endoplasmic reticulum. After the anchor and protein are bound, the anchor attaches itself to the outer surface of the cell membrane, ensuring that the protein will be available when it is needed.


Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.