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VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_018206 Homo sapiens vacuolar protein sorting 35 homolog (S. cerevisiae) (VPS35), mRNA. ORF Sequence $693.39
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Gene Symbol VPS35
Entrez Gene ID 55737
Full Name vacuolar protein sorting 35 homolog (S. cerevisiae)
Synonyms DKFZp434E1211, DKFZp434P1672, FLJ10752, FLJ13588, FLJ20388, MEM3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16q12

Summary This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008].
Disorder

MIM: 601501

mRNA Protein Product Sequence Price Select
NM_018206, 156602659 NP_060676, 17999541 vacuolar protein sorting-associated protein 35 Full Length $1154.30
ORF Sequence $693.39
Homo sapiens (human)VPS35NP_060676.2
Pan troglodytes (chimpanzee)VPS35XP_001161536.1
Macaca mulatta (Rhesus monkey)VPS35XP_001108828.2
Canis lupus familiaris (dog)VPS35XP_532570.3
Bos taurus (cattle)VPS35NP_001039723.1
Mus musculus (house mouse)Vps35NP_075373.1
Rattus norvegicus (Norway rat)Vps35NP_001099188.2
Gallus gallus (chicken)VPS35NP_001005842.1
Danio rerio (zebrafish)vps35NP_001020688.2
Drosophila melanogaster (fruit fly)Vps35NP_611651.4
Caenorhabditis elegansvps-35NP_495180.2
Arabidopsis thaliana (thale cress)VPS35BNP_177713.3
GeneCards VPS35
PDB 2R17
UniProt Q96QK1
MIM 601501
Ensembl ENSG00000069329
HGNC 13487
HPRD 06085

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
vacuolar protein sorting-associated protein 35
Names
vacuolar protein sorting-associated protein 35
hVPS35
maternal-embryonic 3

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