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PRKCD protein kinase C, delta [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_006254 Homo sapiens protein kinase C, delta (PRKCD), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $849.00 20
NM_212539 Homo sapiens protein kinase C, delta (PRKCD), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $849.00 20

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Related Services

Gene Symbol PRKCD
Entrez Gene ID 5580
Full Name protein kinase C, delta
Synonyms MAY1, MGC49908, PKCD, nPKC-delta
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3p21.31

Summary Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
Disorder

MIM: 176977

mRNA Protein Product Sequence Price Select
NM_006254, 47157323 NP_006245, 31377782 protein kinase C delta type ORF Sequence $700.00
NM_212539, 47157324 NP_997704, 47157325 protein kinase C delta type ORF Sequence $700.00
KEGG
hsa04062Chemokine signaling pathway
hsa04912GnRH signaling pathway
hsa04530Tight junction
hsa04666Fc gamma R-mediated phagocytosis
hsa04664Fc epsilon RI signaling pathway
hsa04270Vascular smooth muscle contraction
hsa04930Type II diabetes mellitus
hsa04722Neurotrophin signaling pathway
Pathway Interaction Database
il6_7pathwayIL6-mediated signaling events
txa2pathwayThromboxane A2 receptor signaling
mapktrkpathwayTrk receptor signaling mediated by the MAPK pathway
endothelinpathwayEndothelins
p53regulationpathwayp53 pathway
igf1_pathwayIGF1 pathway
ceramide_pathwayCeramide signaling pathway
lysophospholipid_pathwayLPA receptor mediated events
pi3kplctrkpathwayTrk receptor signaling mediated by PI3K and PLC-gamma
erbb1_downstream_pathwayErbB1 downstream signaling
ifngpathwayIFN-gamma pathway
syndecan_2_pathwaySyndecan-2-mediated signaling events
nfat_3pathwayRole of Calcineurin-dependent NFAT signaling in lymphocytes
pdgfrbpathwayPDGFR-beta signaling pathway
hedgehog_glipathwayHedgehog signaling events mediated by Gli proteins
syndecan_4_pathwaySyndecan-4-mediated signaling events
alphasynuclein_pathwayAlpha-synuclein signaling
WikiPathways
WP23B Cell Receptor Signaling Pathway
WP364IL-6 Signaling Pathway
WP2374Oncostatin M Signaling Pathway
WP289Myometrial Relaxation and Contraction Pathways
WP619Type II interferon signaling (IFNG)
WP2324AGE/RAGE pathway
WP35G Protein Signaling Pathways
WP2012miRs in Muscle Cell Differentiation
WP366TGF-beta Receptor Signaling Pathway
WP69TCR Signaling Pathway
WP244Alpha6-Beta4 Integrin Signaling Pathway
WP2261Signaling Pathways in Glioblastoma
WP1584Type II diabetes mellitus
WP428Wnt Signaling Pathway
WP395IL-4 signaling Pathway
WP481Insulin Signaling
WP399Wnt Signaling Pathway and Pluripotency
WP536Calcium Regulation in the Cardiac Cell
WP127IL-5 Signaling Pathway
WP382MAPK signaling pathway
Reactome
REACT_115871Signaling by EGFR in Cancer
REACT_115720PLCG1 events in ERBB2 signaling
REACT_147814DAP12 signaling
REACT_9417Signaling by EGFR
REACT_25229Interferon Signaling
REACT_14797Signaling by GPCR
REACT_6802Innate Immune System
REACT_15426PLC beta mediated events
REACT_995Apoptotic execution phase
REACT_111102Signal Transduction
REACT_15307Ca-dependent events
REACT_12478EGFR interacts with phospholipase C-gamma
REACT_107Apoptotic cleavage of cellular proteins
REACT_19184GPCR downstream signaling
REACT_115755Signaling by ERBB2
REACT_11061Signalling by NGF
REACT_604Hemostasis
REACT_120736Signaling by FGFR in disease
REACT_25218Stabilization of mRNA by HuR
REACT_24994Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
REACT_17025Downstream signal transduction
REACT_6900Immune System
REACT_71Gene Expression
REACT_111064DAG and IP3 signaling
REACT_19333G alpha (z) signalling events
REACT_147694DAP12 interactions
REACT_15526G-protein mediated events
REACT_2202Effects of PIP2 hydrolysis
REACT_12079PLC-gamma1 signalling
REACT_9000Calmodulin induced events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_75790Cytokine Signaling in Immune system
REACT_798Platelet activation, signaling and aggregation
REACT_21272Downstream signaling of activated FGFR
REACT_116125Disease
REACT_18283G alpha (q) signalling events
REACT_9053CaM pathway
REACT_25078Interferon gamma signaling
REACT_578Apoptosis
REACT_16888Signaling by PDGF
REACT_15295Opioid Signalling
REACT_9470Signaling by FGFR
REACT_21310Phospholipase C-mediated cascade
Homo sapiens (human)PRKCDNP_006245.2
Pan troglodytes (chimpanzee)PRKCDXP_003309918.2
Macaca mulatta (Rhesus monkey)LOC694656XP_001083320.1
Canis lupus familiaris (dog)PRKCDNP_001008716.1
Bos taurus (cattle)PRKCDNP_001071323.1
Mus musculus (house mouse)PrkcdNP_035233.1
Rattus norvegicus (Norway rat)PrkcdNP_579841.1
Gallus gallus (chicken)PRKCDNP_001006133.1
Danio rerio (zebrafish)LOC100150844XP_001919906.3
Danio rerio (zebrafish)prkcdaNP_999873.1
Drosophila melanogaster (fruit fly)PkcdeltaNP_511171.3
Caenorhabditis eleganstpa-1NP_499860.1
GeneCards PRKCD
PDB 1YRK, 2YUU
UniProt Q05655
MIM 176977
Ensembl ENSG00000163932
HGNC 9399
HPRD 01501

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
protein kinase C delta type
Names
protein kinase C delta type
protein kinase C delta VIII
tyrosine-protein kinase PRKCD
NP_006245.2
NP_997704.1

Interactant



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