PRL prolactin [Homo sapiens (human)]
| Gene Symbol | PRL |
| Entrez Gene ID | 5617 |
| Full Name | prolactin |
| Synonyms | |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
6 6p22.2-p21.3 |
| Summary | |
| Disorder | MIM: 176760 |
| mRNA | NM_001163558, 254675132 |
| Protein | NP_001157030, 254675133 |
| Product | prolactin precursor |
| RefSeq Status | VALIDATED |
| mRNA | NM_000948, 254281326 |
| Protein | NP_000939, 4506105 |
| Product | prolactin precursor |
| RefSeq Status | VALIDATED |
| hsa04630 | Jak-STAT signaling pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04060 | Cytokine-cytokine receptor interaction |
WikiPathways
| WP98 | Prostaglandin Synthesis and Regulation |
Pathway Interaction Database
| ptp1bpathway | Signaling events mediated by PTP1B |
| erbb4_pathway | ErbB4 signaling events |
| reg_gr_pathway | Glucocorticoid receptor regulatory network |
| Homo sapiens (human) | PRL | NP_001157030.1 |
| Pan troglodytes (chimpanzee) | PRL | XP_001171378.1 |
| Canis lupus familiaris (dog) | PRL | XP_545363.2 |
| Bos taurus (cattle) | PRL | NP_776378.2 |
| Mus musculus (house mouse) | Prl | NP_035294.1 |
| Rattus norvegicus (Norway rat) | Prl | NP_036761.1 |
| Gallus gallus (chicken) | PRL | NP_990797.1 |
| ID | Name | Evidence |
| GO:0007166 | cell surface receptor linked signaling pathway | TAS |
| GO:0007565 | female pregnancy | NAS |
| GO:0007595 | lactation | IEA |
| GO:0008283 | cell proliferation | TAS |
| GO:0040014 | regulation of multicellular organism growth | IEP |
| GO:0046427 | positive regulation of JAK-STAT cascade | IDA |
Component
| ID | Name | Evidence |
| GO:0005576 | extracellular region | IEA |
| GO:0005829 | cytosol | TAS |
Function
| ID | Name | Evidence |
| GO:0005148 | prolactin receptor binding | TAS |
| GO:0005179 | hormone activity | IEA |
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