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RTN4 reticulon 4 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_007008 Homo sapiens reticulon 4 (RTN4), transcript variant 3, mRNA. ORF Sequence $174.00
Peptide Services
Antibody Services
Protein Services
NM_020532 Homo sapiens reticulon 4 (RTN4), transcript variant 1, mRNA. ORF Sequence $1252.65
Peptide Services
Antibody Services
Protein Services
NM_153828 Homo sapiens reticulon 4 (RTN4), transcript variant 2, mRNA. ORF Sequence $325.38
Peptide Services
Antibody Services
Protein Services
NM_207520 Homo sapiens reticulon 4 (RTN4), transcript variant 4, mRNA. ORF Sequence $341.91
Peptide Services
Antibody Services
Protein Services
NM_207521 Homo sapiens reticulon 4 (RTN4), transcript variant 5, mRNA. ORF Sequence $858.69
Peptide Services
Antibody Services
Protein Services


Gene Symbol RTN4
Entrez Gene ID 57142
Full Name reticulon 4
Synonyms ASY, NI220/250, NOGO, NOGO-A, NOGOC, NSP, NSP-CL, Nbla00271, Nbla10545, Nogo-B, Nogo-C, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p16.3

Summary This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Disorder

MIM: 604475

mRNA Protein Product Sequence Price Select
NM_007008, 47519538 NP_008939, 5902016 reticulon-4 isoform C Full Length $524.32
ORF Sequence $174.00
NM_020532, 47519458 NP_065393, 24431935 reticulon-4 isoform A Full Length $1704.85
ORF Sequence $1252.65
NM_153828, 47519507 NP_722550, 24431933 reticulon-4 isoform B Full Length $700.06
ORF Sequence $325.38
NM_207520, 47519489 NP_997403, 47519490 reticulon-4 isoform D Full Length $716.59
ORF Sequence $341.91
NM_207521, 47519561 NP_997404, 47519562 reticulon-4 isoform E Full Length $1445.15
ORF Sequence $858.69
Pathway Interaction Database
p75ntrpathwayp75(NTR)-mediated signaling
Reactome
REACT_13620p75NTR regulates axonogenesis
REACT_111102Signal Transduction
REACT_11061Signalling by NGF
REACT_13776p75 NTR receptor-mediated signalling
REACT_13815Axonal growth inhibition (RHOA activation)
Homo sapiens (human)RTN4NP_065393.1
Macaca mulatta (Rhesus monkey)RTN4XP_001112090.2
Canis lupus familiaris (dog)RTN4XP_531828.2
Mus musculus (house mouse)Rtn4NP_918943.1
Rattus norvegicus (Norway rat)Rtn4NP_114019.1
Gallus gallus (chicken)RTN4XP_003640941.1
GeneCards RTN4
PDB 2G31, 2JV5
UniProt Q9NQC3
MIM 604475
Ensembl ENSG00000115310
HGNC 14085
HPRD 07259

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
reticulon-4
Names
reticulon-4
foocen
Human NogoA
reticulon 5
My043 protein
neurite outgrowth inhibitor
neurite growth inhibitor 220
neuroendocrine-specific protein C homolog

Interactant

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