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Sequence in raw or FASTA format:


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RAG1 recombination activating gene 1 [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu17854D NM_000448 Homo sapiens recombination activating gene 1 (RAG1), mRNA. pcDNA3.1-C-(k)DYK In-stock 16 Starting from $99
OHu44935D XM_005253041 PREDICTED: Homo sapiens recombination activating gene 1 (RAG1), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK On-demand 20 Starting from $99
OHu17854C NM_000448 Homo sapiens recombination activating gene 1 (RAG1), mRNA. Customized vector In-stock 16 Starting from $99
OHu44935C XM_005253041 PREDICTED: Homo sapiens recombination activating gene 1 (RAG1), transcript variant X1, mRNA. Customized vector On-demand 20 Starting from $99

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Gene Symbol RAG1
Entrez Gene ID 5896
Full Name recombination activating gene 1
Synonyms RAG-1, RNF74
General protein information
Preferred Names
V(D)J recombination-activating protein 1
V(D)J recombination-activating protein 1
RING finger protein 74
recombination activating protein 1
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases. [provided by RefSeq, Jul 2008].

MIM: 179615

Severe combined immunodeficiency, B cell-negative, 601457 (3);

mRNA Protein Product Sequence Price Select
NM_000448, 172072669 NP_000439, 4557841 V(D)J recombination-activating protein 1 ORF Sequence $999.00
XM_005253041, 578820674 XP_005253098, 530395605 V(D)J recombination-activating protein 1 isoform X1 ORF Sequence $1500.00
hsa05340Primary immunodeficiency
hsa04068FoxO signaling pathway
Homo sapiens (human)RAG1NP_000439.1
Pan troglodytes (chimpanzee)RAG1XP_001154240.1
Macaca mulatta (Rhesus monkey)RAG1XP_001084631.1
Canis lupus familiaris (dog)RAG1XP_540538.1
Bos taurus (cattle)RAG1XP_005216456.1
Mus musculus (house mouse)Rag1NP_033045.2
Rattus norvegicus (Norway rat)Rag1NP_445920.1
Gallus gallus (chicken)RAG1NP_001026359.1
Danio rerio (zebrafish)rag1NP_571464.1
Xenopus (Silurana) tropicalis (western clawed frog)rag1XP_002937338.1
GO:0002250adaptive immune responseIEA
GO:0002331pre-B cell allelic exclusionISS
GO:0006310DNA recombinationTAS
GO:0006955immune responseTAS
GO:0010390histone monoubiquitinationISS
GO:0030183B cell differentiationISS
GO:0033077T cell differentiation in thymusISS
GO:0033151V(D)J recombinationISS
GO:0043029T cell homeostasisIEA
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic processIEA
GO:0045580regulation of T cell differentiationIEA
GO:0048538thymus developmentIEA
GO:0051865protein autoubiquitinationISS
GO:0070244negative regulation of thymocyte apoptotic processIEA
GO:0090305nucleic acid phosphodiester bond hydrolysisIEA
GO:0090305nucleic acid phosphodiester bond hydrolysisISS
GO:0003677DNA bindingTAS
GO:0004519endonuclease activityISS
GO:0004842ubiquitin-protein transferase activityISS
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingISS
GO:0016881acid-amino acid ligase activityIEA
GO:0042393histone bindingISS
GO:0042803protein homodimerization activityISS
GO:0043565sequence-specific DNA bindingISS
GO:0046872metal ion bindingISS
GeneCards RAG1
UniProt P15918
Vega OTTHUMG00000166392
MIM 179615
Ensembl ENSG00000166349
HGNC 9831
HPRD 01556

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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