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RARA retinoic acid receptor, alpha [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000964 Homo sapiens retinoic acid receptor, alpha (RARA), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001024809 Homo sapiens retinoic acid receptor, alpha (RARA), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001145301 Homo sapiens retinoic acid receptor, alpha (RARA), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001145302 Homo sapiens retinoic acid receptor, alpha (RARA), transcript variant 4, mRNA. GenEZ ORF Cloning On-demand TBD TBD

*Business Day

Related Services

Gene Symbol RARA
Entrez Gene ID 5914
Full Name retinoic acid receptor, alpha
Synonyms NR1B1, RAR
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q21

Summary This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010].
Disorder

MIM: 180240

Leukemia, acute promyelocytic, 612376 (1)

mRNA Protein Product Sequence Price Select
NM_000964, 300388174 NP_000955, 4506419 retinoic acid receptor alpha isoform 1 ORF Sequence $550.00
NM_001024809, 300388162 NP_001019980, 67459914 retinoic acid receptor alpha isoform 2 ORF Sequence $550.00
NM_001145301, 300388161 NP_001138773, 223718064 retinoic acid receptor alpha isoform 1 ORF Sequence $550.00
NM_001145302, 300388173 NP_001138774, 223718070 retinoic acid receptor alpha isoform 4 ORF Sequence $400.00
KEGG
hsa05202Transcriptional misregulation in cancer
hsa05221Acute myeloid leukemia
hsa05200Pathways in cancer
Pathway Interaction Database
retinoic_acid_pathwayRetinoic acid receptors-mediated signaling
WikiPathways
WP716Vitamin A and carotenoid metabolism
WP299Nuclear receptors in lipid metabolism and toxicity
WP236Adipogenesis
WP170Nuclear Receptors
WP2377Integrated Pancreatic Cancer Pathway
WP286IL-3 Signaling Pathway
WP2256Integrated Pancreatic Cancer Pathway
Reactome
REACT_12627Generic Transcription Pathway
REACT_71Gene Expression
REACT_15525Nuclear Receptor transcription pathway
Homo sapiens (human)RARANP_001019980.1
Pan troglodytes (chimpanzee)RARAXP_003315498.2
Macaca mulatta (Rhesus monkey)RARAXP_002808174.1
Canis lupus familiaris (dog)RARANP_001012663.1
Bos taurus (cattle)RARANP_001014942.2
Mus musculus (house mouse)RaraNP_001170773.1
Rattus norvegicus (Norway rat)RaraNP_113716.2
Gallus gallus (chicken)RARANP_989867.1
Danio rerio (zebrafish)rarabNP_571474.1
Danio rerio (zebrafish)raraaNP_571481.2
GeneCards RARA
PDB 3KMR, 3A9E, 1DSZ, 3KMZ, 1DKF, 4DQM
UniProt F1D8N9, A8K840, Q6I9R7, P10276
MIM 180240
Ensembl ENSG00000131759
HGNC 9864
HPRD 06769

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
retinoic acid receptor alpha
Names
retinoic acid receptor alpha
RAR-alpha
retinoic acid receptor, alpha polypeptide
nuclear receptor subfamily 1 group B member 1
retinoic acid nuclear receptor alpha variant 1
retinoic acid nuclear receptor alpha variant 2
nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form

Interactant



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