Search Tips

  • THAT   AND
  • THAT   AND


HPSE2 heparanase 2 [Homo sapiens (human)]


RefSeq Accession Definition Sequence Price Select
NM_021828 Homo sapiens heparanase 2 (HPSE2), transcript variant 1, mRNA. Full Length $1522.15
ORF Sequence $515.91
NM_001166244 Homo sapiens heparanase 2 (HPSE2), transcript variant 2, mRNA. Full Length $1461.25
ORF Sequence $465.45
NM_001166245 Homo sapiens heparanase 2 (HPSE2), transcript variant 3, mRNA. Full Length $1404.55
ORF Sequence $418.47
NM_001166246 Homo sapiens heparanase 2 (HPSE2), transcript variant 4, mRNA. Full Length $1546.65
ORF Sequence $477.63


Gene Symbol HPSE2
Entrez Gene ID 60495
Full Name heparanase 2
Synonyms FLJ11684, FLJ44022, HPA2, HPR2, MGC133234, UFS
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10q23-q24
Summary This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
Disorder

MIM: 613469

Urofacial syndrome, 236730 (3)
mRNA NM_021828, 261878500
Protein NP_068600, 261878501
Product heparanase-2 isoform 1
RefSeq Status REVIEWED
mRNA NM_001166244, 261878502
Protein NP_001159716, 261878503
Product heparanase-2 isoform 2
RefSeq Status REVIEWED
mRNA NM_001166245, 261878504
Protein NP_001159717, 261878505
Product heparanase-2 isoform 3
RefSeq Status REVIEWED
mRNA NM_001166246, 261878506
Protein NP_001159718, 261878507
Product heparanase-2 isoform 4
RefSeq Status REVIEWED
KEGG
hsa01100Metabolic pathways
hsa00531Glycosaminoglycan degradation
Homo sapiens (human)HPSE2NP_068600.4
Pan troglodytes (chimpanzee)HPSE2XP_001166372.1
Canis lupus familiaris (dog)HPSE2XP_850311.1
Bos taurus (cattle)HPSE2XP_617505.4
Mus musculus (house mouse)Hpse2NP_001074726.1
Rattus norvegicus (Norway rat)Hpse2XP_347297.3
Gallus gallus (chicken)HPSE2XP_421704.2
Danio rerio (zebrafish)si:dkeyp-22h2.2XP_691045.2
Process
IDNameEvidence
GO:0005975carbohydrate metabolic processIEA
GO:0008150biological_processND
Component
IDNameEvidence
GO:0005622intracellularTAS
GO:0016020membraneIEA
Function
IDNameEvidence
GO:0016798hydrolase activity, acting on glycosyl bondsIEA
GO:0030305heparanase activityTAS
GO:0043169cation bindingIEA
GeneCards HPSE2
UniProt Q8WWQ2, Q2M1H9
MIM 613469
Ensembl ENSG00000172987
HGNC 18374
HPRD 13669

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Secured Online Quotation
Email: gene@genscript.com
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Fax: 1-732-210-0262 1-732-885-5878