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RPS10 ribosomal protein S10 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001014 Homo sapiens ribosomal protein S10 (RPS10), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10
NM_001203245 Homo sapiens ribosomal protein S10 (RPS10), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10
NM_001204091 Homo sapiens ribosomal protein S10 (RPS10), transcript variant 3, mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10

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Related Services

Gene Symbol RPS10
Entrez Gene ID 6204
Full Name ribosomal protein S10
Synonyms DBA9, S10
General protein information
Preferred Names
40S ribosomal protein S10
Names
40S ribosomal protein S10
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p21.31

Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).[provided by RefSeq, Feb 2011].
Disorder

MIM: 603632

Diamond-Blackfan anemia 9, 613308 (3)

mRNA Protein Product Sequence Price Select
NM_001014, 322303055 NP_001005, 4506679 40S ribosomal protein S10 ORF Sequence $159.00
NM_001203245, 323276698 NP_001190174, 322303127 40S ribosomal protein S10 ORF Sequence $159.00
NM_001204091, 323276699 NP_001191020, 323276700 40S ribosomal protein S10 ORF Sequence $159.00
KEGG
hsa03010Ribosome
hsa_M00177Ribosome, eukaryotes
WikiPathways
WP477Cytoplasmic Ribosomal Proteins
Reactome
REACT_71Gene Expression
REACT_2159Eukaryotic Translation Initiation
REACT_1979Translation initiation complex formation
REACT_1404Peptide chain elongation
REACT_1258Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REACT_2085GTP hydrolysis and joining of the 60S ribosomal subunit
REACT_1079Formation of the ternary complex, and subsequently, the 43S complex
REACT_1477Eukaryotic Translation Elongation
REACT_2099Cap-dependent Translation Initiation
REACT_931Ribosomal scanning and start codon recognition
REACT_1797Formation of a pool of free 40S subunits
REACT_1014Translation
REACT_6145Influenza Life Cycle
REACT_9491Viral mRNA Translation
REACT_6152Influenza Viral RNA Transcription and Replication
REACT_1986Eukaryotic Translation Termination
REACT_6167Influenza Infection
REACT_17015Metabolism of proteins
REACT_79L13a-mediated translational silencing of Ceruloplasmin expression
REACT_75768Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
REACT_75822Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
REACT_75886Nonsense-Mediated Decay (NMD)
REACT_116125Disease
REACT_115902SRP-dependent cotranslational protein targeting to membrane
Homo sapiens (human)RPS10NP_001005.1
Pan troglodytes (chimpanzee)LOC742827XP_003313051.1
Macaca mulatta (Rhesus monkey)RPS10XP_001116498.1
Canis lupus familiaris (dog)RPS10NP_001238974.1
Bos taurus (cattle)RPS10NP_001029888.1
Mus musculus (house mouse)Rps10NP_080239.1
Rattus norvegicus (Norway rat)Rps10l1XP_002729669.1
Rattus norvegicus (Norway rat)Rps10NP_112371.1
Gallus gallus (chicken)RPS10NP_001244226.1
Drosophila melanogaster (fruit fly)RpS10aNP_651576.1
Process
IDNameEvidence
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTAS
GO:0006412translationIC
GO:0006412translationTAS
GO:0006413translational initiationTAS
GO:0006414translational elongationTAS
GO:0006415translational terminationTAS
GO:0006614SRP-dependent cotranslational protein targeting to membraneTAS
GO:0010467gene expressionTAS
GO:0016032viral processTAS
GO:0016070RNA metabolic processTAS
GO:0016071mRNA metabolic processTAS
GO:0019058viral life cycleTAS
GO:0019083viral transcriptionTAS
GO:0044267cellular protein metabolic processTAS
Component
IDNameEvidence
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005829cytosolTAS
GO:0005840ribosomeNAS
GO:0016020membraneIDA
GO:0022627cytosolic small ribosomal subunitIDA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0044822poly(A) RNA bindingIDA
GeneCards RPS10
PDB 3J3A
UniProt P46783
Vega OTTHUMG00000014546
MIM 603632
Ensembl ENSG00000124614
HGNC 10383
HPRD 04697

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the RPS10 gene?

The RPS10 gene provides instructions for making one of approximately 80 different ribosomal proteins, which are components of cellular structures called ribosomes. Ribosomes process the cell's genetic instructions to create proteins.

Each ribosome is made up of two parts (subunits) called the large and small subunits. The protein produced from the RPS10 gene is among those found in the small subunit.

The specific functions of the RPS10 protein and the other ribosomal proteins within these subunits are unclear. Some ribosomal proteins are involved in the assembly or stability of ribosomes. Others help carry out the ribosome's main function of building new proteins. Studies suggest that some ribosomal proteins may have other functions, such as participating in chemical signaling pathways within the cell, regulating cell division, and controlling the self-destruction of cells (apoptosis).

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