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RPS13 ribosomal protein S13 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001017 Homo sapiens ribosomal protein S13 (RPS13), mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10

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Gene Symbol RPS13
Entrez Gene ID 6207
Full Name ribosomal protein S13
Synonyms S13
General protein information
Preferred Names
40S ribosomal protein S13
Names
40S ribosomal protein S13
NP_001008.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p15

Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S15P family of ribosomal proteins. It is located in the cytoplasm. The protein has been shown to bind to the 5.8S rRNA in rat. The gene product of the E. coli ortholog (ribosomal protein S15) functions at early steps in ribosome assembly. This gene is co-transcribed with two U14 small nucleolar RNA genes, which are located in its third and fifth introns. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
Disorder

MIM: 180476

mRNA Protein Product Sequence Price Select
NM_001017, 14591910 NP_001008, 4506685 40S ribosomal protein S13 ORF Sequence $99.00
KEGG
hsa03010Ribosome
hsa_M00177Ribosome, eukaryotes
WikiPathways
WP477Cytoplasmic Ribosomal Proteins
WP231TNF-alpha/NF-kB Signaling Pathway
Reactome
REACT_71Gene Expression
REACT_2159Eukaryotic Translation Initiation
REACT_1404Peptide chain elongation
REACT_1258Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REACT_1979Translation initiation complex formation
REACT_2085GTP hydrolysis and joining of the 60S ribosomal subunit
REACT_1079Formation of the ternary complex, and subsequently, the 43S complex
REACT_1477Eukaryotic Translation Elongation
REACT_2099Cap-dependent Translation Initiation
REACT_931Ribosomal scanning and start codon recognition
REACT_1797Formation of a pool of free 40S subunits
REACT_1014Translation
REACT_6145Influenza Life Cycle
REACT_9491Viral mRNA Translation
REACT_6152Influenza Viral RNA Transcription and Replication
REACT_1986Eukaryotic Translation Termination
REACT_6167Influenza Infection
REACT_17015Metabolism of proteins
REACT_79L13a-mediated translational silencing of Ceruloplasmin expression
REACT_75768Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
REACT_75822Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
REACT_75886Nonsense-Mediated Decay (NMD)
REACT_116125Disease
REACT_115902SRP-dependent cotranslational protein targeting to membrane
Homo sapiens (human)RPS13NP_001008.1
Pan troglodytes (chimpanzee)RPS13XP_003312983.1
Macaca mulatta (Rhesus monkey)RPS13XP_001086088.1
Canis lupus familiaris (dog)RPS13XP_864902.1
Bos taurus (cattle)RPS13NP_001020513.1
Mus musculus (house mouse)Rps13NP_080809.1
Gallus gallus (chicken)RPS13NP_001001783.1
Danio rerio (zebrafish)rps13NP_001002079.1
Drosophila melanogaster (fruit fly)RpS13NP_476938.1
Caenorhabditis elegansrps-13NP_498393.1
Arabidopsis thaliana (thale cress)AT3G60770NP_567104.1
Arabidopsis thaliana (thale cress)RPS13ANP_567151.1
Xenopus (Silurana) tropicalis (western clawed frog)rps13NP_001016602.1
Process
IDNameEvidence
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTAS
GO:0006412translationIC
GO:0006412translationTAS
GO:0006413translational initiationTAS
GO:0006414translational elongationTAS
GO:0006415translational terminationTAS
GO:0006614SRP-dependent cotranslational protein targeting to membraneTAS
GO:0010467gene expressionTAS
GO:0016032viral processTAS
GO:0016070RNA metabolic processTAS
GO:0016071mRNA metabolic processTAS
GO:0019058viral life cycleTAS
GO:0019083viral transcriptionTAS
GO:0033119negative regulation of RNA splicingIDA
GO:0044267cellular protein metabolic processTAS
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005730nucleolusIDA
GO:0005829cytosolTAS
GO:0005840ribosomeNAS
GO:0016020membraneIDA
GO:0022627cytosolic small ribosomal subunitIDA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0003729mRNA bindingIDA
GO:0003735structural constituent of ribosomeIEA
GO:0005515protein bindingIPI
GO:0044822poly(A) RNA bindingIDA
GeneCards RPS13
PDB 3J3A
UniProt P62277
Vega OTTHUMG00000165988
MIM 180476
Ensembl ENSG00000110700
HGNC 10386
HPRD 01604

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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