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RPS17 ribosomal protein S17 [Homo sapiens (human)]


RefSeq Accession Definition Sequence Price Select
NM_001021 Homo sapiens ribosomal protein S17 (RPS17), mRNA. Full Length $159.00
ORF Sequence $159.00


Gene Symbol RPS17
Entrez Gene ID 6218
Full Name ribosomal protein S17
Synonyms DBA4, MGC72007, RPS17L1, RPS17L2, S17
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].
Disorder

MIM: 180472

Diamond-Blackfan anemia 4, 612527 (3)
mRNA NM_001021, 71772428
Protein NP_001012, 4506693
Product 40S ribosomal protein S17
RefSeq Status REVIEWED
KEGG
hsa03010Ribosome
WikiPathways
WP477Cytoplasmic Ribosomal Proteins
Reactome
REACT_17015Metabolism of proteins
REACT_13819Regulation of gene expression in beta cells
REACT_1986Eukaryotic Translation Termination
REACT_1079Formation of the ternary complex, and subsequently, the 43S complex
REACT_79L13a-mediated translational silencing of Ceruloplasmin expression
REACT_2159Eukaryotic Translation Initiation
REACT_1979Translation initiation complex formation
REACT_2085GTP hydrolysis and joining of the 60S ribosomal subunit
REACT_15380Diabetes pathways
REACT_9491Viral mRNA Translation
REACT_6145Influenza Life Cycle
REACT_1404Peptide chain elongation
REACT_71Gene Expression
REACT_1797Formation of a pool of free 40S subunits
REACT_1258Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REACT_1014Translation
REACT_931Ribosomal scanning and start codon recognition
REACT_6167Influenza Infection
REACT_2099Cap-dependent Translation Initiation
REACT_6152Influenza Viral RNA Transcription and Replication
REACT_13698Regulation of beta-cell development
REACT_15550Insulin Synthesis and Processing
REACT_1477Eukaryotic Translation Elongation
Homo sapiens (human)RPS17NP_001012.1
Homo sapiens (human)LOC100505503XP_003119059.1
Pan troglodytes (chimpanzee)RPS17XP_001151485.1
Canis lupus familiaris (dog)RPS17NP_001003099.1
Bos taurus (cattle)RPS17NP_001092680.1
Mus musculus (house mouse)Gm12034XP_985520.2
Rattus norvegicus (Norway rat)RGD1559955XP_346082.3
Gallus gallus (chicken)RPS17NP_989548.1
Danio rerio (zebrafish)zgc:77702NP_957139.1
Drosophila melanogaster (fruit fly)RpS17NP_524002.1
Process
IDNameEvidence
GO:0000028ribosomal small subunit assemblyISS
GO:0006364rRNA processingIMP
GO:0006412translationIC
GO:0006412translationTAS
GO:0006413translational initiationNAS
GO:0006414translational elongationEXP
GO:0006414translational elongationISS
GO:0006415translational terminationTAS
GO:0010467gene expressionTAS
GO:0016032viral reproductionTAS
GO:0019058viral infectious cycleTAS
GO:0019083viral transcriptionTAS
GO:0031018endocrine pancreas developmentTAS
GO:0034101erythrocyte homeostasisIMP
GO:0042274ribosomal small subunit biogenesisIMP
GO:0044267cellular protein metabolic processTAS
Component
IDNameEvidence
GO:0005622intracellularIEA
GO:0005829cytosolEXP
GO:0005829cytosolTAS
GO:0005840ribosomeNAS
GO:0022627cytosolic small ribosomal subunitIDA
GO:0022627cytosolic small ribosomal subunitISS
Function
IDNameEvidence
GO:0003735structural constituent of ribosomeNAS
GeneCards RPS17
MIM 180472
Ensembl ENSG00000184779
HGNC 10397
HPRD 01600

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