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RPS26 ribosomal protein S26 [Homo sapiens (human)]


RefSeq Accession Definition Sequence Price Select
NM_001029 Homo sapiens ribosomal protein S26 (RPS26), mRNA. Full Length $202.71
ORF Sequence $159.00


Gene Symbol RPS26
Entrez Gene ID 6231
Full Name ribosomal protein S26
Synonyms DBA10, MGC104292, S26
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q13
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S26E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].
Disorder

MIM: 603701

Diamond-Blackfan anemia 10, 613309 (3)
mRNA NM_001029, 71559137
Protein NP_001020, 15011936
Product 40S ribosomal protein S26
RefSeq Status REVIEWED
KEGG
hsa03010Ribosome
WikiPathways
WP477Cytoplasmic Ribosomal Proteins
Reactome
REACT_9491Viral mRNA Translation
REACT_1404Peptide chain elongation
REACT_1258Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REACT_13698Regulation of beta-cell development
REACT_79L13a-mediated translational silencing of Ceruloplasmin expression
REACT_6167Influenza Infection
REACT_2099Cap-dependent Translation Initiation
REACT_15550Insulin Synthesis and Processing
REACT_1477Eukaryotic Translation Elongation
REACT_17015Metabolism of proteins
REACT_1079Formation of the ternary complex, and subsequently, the 43S complex
REACT_1014Translation
REACT_6152Influenza Viral RNA Transcription and Replication
REACT_931Ribosomal scanning and start codon recognition
REACT_1986Eukaryotic Translation Termination
REACT_1979Translation initiation complex formation
REACT_13819Regulation of gene expression in beta cells
REACT_15380Diabetes pathways
REACT_2159Eukaryotic Translation Initiation
REACT_6145Influenza Life Cycle
REACT_2085GTP hydrolysis and joining of the 60S ribosomal subunit
REACT_71Gene Expression
REACT_1797Formation of a pool of free 40S subunits
Homo sapiens (human)RPS26NP_001020.2
Canis lupus familiaris (dog)RPS26XP_531628.1
Bos taurus (cattle)RPS26NP_001015561.1
Mus musculus (house mouse)Rps26NP_038793.1
Rattus norvegicus (Norway rat)Rps26NP_037356.1
Danio rerio (zebrafish)rps26lNP_957036.1
Danio rerio (zebrafish)rps26NP_956319.1
Drosophila melanogaster (fruit fly)RpS26NP_724110.1
Caenorhabditis elegansrps-26NP_493571.1
Arabidopsis thaliana (thale cress)AT3G56340NP_191193.1
Arabidopsis thaliana (thale cress)AT2G40510NP_181583.1
Arabidopsis thaliana (thale cress)AT2G40590NP_181591.1
Process
IDNameEvidence
GO:0006412translationIC
GO:0006412translationTAS
GO:0006414translational elongationEXP
GO:0006415translational terminationTAS
GO:0010467gene expressionTAS
GO:0016032viral reproductionTAS
GO:0019058viral infectious cycleTAS
GO:0019083viral transcriptionTAS
GO:0031018endocrine pancreas developmentTAS
GO:0033119negative regulation of RNA splicingIDA
GO:0044267cellular protein metabolic processTAS
Component
IDNameEvidence
GO:0005622intracellularIEA
GO:0005829cytosolEXP
GO:0005829cytosolTAS
GO:0015935small ribosomal subunitIDA
GO:0022627cytosolic small ribosomal subunitIDA
Function
IDNameEvidence
GO:0003729mRNA bindingIDA
GO:0003735structural constituent of ribosomeIEA
GO:0005515protein bindingIPI
GeneCards RPS26
UniProt P62854
MIM 603701
Ensembl ENSG00000197728
HGNC 10414
HPRD 04743

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