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RYR2 ryanodine receptor 2 (cardiac) [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001035 Homo sapiens ryanodine receptor 2 (cardiac) (RYR2), mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Gene Symbol RYR2
Entrez Gene ID 6262
Full Name ryanodine receptor 2 (cardiac)
Synonyms ARVC2, ARVD2, VTSIP
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008].

MIM: 180902

Ventricular tachycardia, catecholaminergic polymorphic, 1, 604772

mRNA Protein Product Sequence Price Select
NM_001035, 112799846 NP_001026, 112799847 ryanodine receptor 2 ORF Sequence $-1.00
hsa05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa04972Pancreatic secretion
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa04713Circadian entrainment
hsa05414Dilated cardiomyopathy
hsa04020Calcium signaling pathway
hsa04260Cardiac muscle contraction
WP536Calcium Regulation in the Cardiac Cell
WP2118Arrhythmogenic right ventricular cardiomyopathy
WP706SIDS Susceptibility Pathways
WP289Myometrial Relaxation and Contraction Pathways
Homo sapiens (human)RYR2NP_001026.2
Pan troglodytes (chimpanzee)RYR2XP_514296.4
Macaca mulatta (Rhesus monkey)RYR2XP_002808310.1
Canis lupus familiaris (dog)RYR2XP_536330.3
Bos taurus (cattle)RYR2XP_002698859.1
Mus musculus (house mouse)Ryr2NP_076357.2
Rattus norvegicus (Norway rat)Ryr2NP_114467.1
Gallus gallus (chicken)RYR2XP_419553.3
Danio rerio (zebrafish)ryr2bXP_001921137.1
Drosophila melanogaster (fruit fly)Rya-r44FNP_476991.1
Caenorhabditis elegansunc-68NP_504753.3
GeneCards RYR2
UniProt Q92736
MIM 180902
Ensembl ENSG00000198626
HGNC 10484
HPRD 01619

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
ryanodine receptor 2
ryanodine receptor 2
type 2 ryanodine receptor
islet-type ryanodine receptor
kidney-type ryanodine receptor
cardiac-type ryanodine receptor
cardiac muscle ryanodine receptor-calcium release channel


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