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SAA1 serum amyloid A1 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000331 Homo sapiens serum amyloid A1 (SAA1), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10
NM_001178006 Homo sapiens serum amyloid A1 (SAA1), transcript variant 3, mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10
NM_199161 Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10

*Business Day

Related Services

Gene Symbol SAA1
Entrez Gene ID 6288
Full Name serum amyloid A1
Synonyms MGC111216, PIG4, SAA, SAA2, TP53I4
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012].

MIM: 104750

mRNA Protein Product Sequence Price Select
NM_000331, 295821191 NP_000322, 40316912 serum amyloid A-1 protein preproprotein ORF Sequence $99.00
NM_001178006, 295821192 NP_001171477, 295821193 serum amyloid A-1 protein preproprotein ORF Sequence $99.00
NM_199161, 295821190 NP_954630, 40316910 serum amyloid A-1 protein preproprotein ORF Sequence $99.00
WP176Folate Metabolism
WP15Selenium Pathway
REACT_118823Cytosolic sensors of pathogen-associated DNA
REACT_21340GPCR ligand binding
REACT_21281TAK1 activates NFkB by phosphorylation and activation of IKKs complex
REACT_25195Advanced glycosylation endproduct receptor signaling
REACT_6890Activated TLR4 signalling
REACT_6788MyD88:Mal cascade initiated on plasma membrane
REACT_6900Immune System
REACT_9047Toll Like Receptor 9 (TLR9) Cascade
REACT_6894Toll Like Receptor 4 (TLR4) Cascade
REACT_6783Toll Like Receptor 3 (TLR3) Cascade
REACT_25359RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_19231G alpha (i) signalling events
REACT_25222MyD88 dependent cascade initiated on endosome
REACT_6966Toll Receptor Cascades
REACT_118764DAI mediated induction of type I IFNs
REACT_6809MyD88-independent cascade
REACT_111102Signal Transduction
REACT_118563RIP-mediated NFkB activation via DAI
REACT_7980Toll Like Receptor 2 (TLR2) Cascade
REACT_9061Toll Like Receptor 5 (TLR5) Cascade
REACT_14797Signaling by GPCR
REACT_8006Toll Like Receptor TLR6:TLR2 Cascade
REACT_14819Peptide ligand-binding receptors
REACT_9027Toll Like Receptor 10 (TLR10) Cascade
REACT_18283G alpha (q) signalling events
REACT_24969TRAF6 mediated NF-kB activation
REACT_27215MyD88 cascade initiated on plasma membrane
REACT_8005Toll Like Receptor TLR1:TLR2 Cascade
REACT_19184GPCR downstream signaling
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_21264Formyl peptide receptors bind formyl peptides and many other ligands
REACT_6802Innate Immune System
REACT_25024TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
REACT_9020Toll Like Receptor 7/8 (TLR7/8) Cascade
REACT_25281NFkB and MAP kinases activation mediated by TLR4 signaling repertoire
Homo sapiens (human)SAA1NP_000322.2
Macaca mulatta (Rhesus monkey)SAA1XP_001086242.1
Macaca mulatta (Rhesus monkey)LOC694944XP_001086477.1
Canis lupus familiaris (dog)LOC100684663XP_003432981.1
Canis lupus familiaris (dog)SAA1XP_534081.1
Bos taurus (cattle)SAA1XP_002699134.1
Bos taurus (cattle)SAA2NP_001068728.1
Mus musculus (house mouse)Saa1NP_033143.1
Mus musculus (house mouse)Saa2NP_035444.1
Danio rerio (zebrafish)saaNP_001005599.1
GeneCards SAA1
UniProt P0DJI8
MIM 104750
Ensembl ENSG00000173432
HGNC 10513
HPRD 00097

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
serum amyloid A-1 protein
serum amyloid A-1 protein
serum amyloid A protein
tumor protein p53 inducible protein 4


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