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SCNN1B sodium channel, non-voltage-gated 1, beta subunit [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18452 NM_000336 Homo sapiens sodium channel, non-voltage-gated 1, beta subunit (SCNN1B), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu49174 XM_005255467 PREDICTED: Homo sapiens sodium channel, non-voltage-gated 1, beta subunit (SCNN1B), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu18452C NM_000336 Homo sapiens sodium channel, non-voltage-gated 1, beta subunit (SCNN1B), mRNA. Customized vector On-demand 7-9 $269.00
OHu49174C XM_005255467 PREDICTED: Homo sapiens sodium channel, non-voltage-gated 1, beta subunit (SCNN1B), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol SCNN1B
Entrez Gene ID 6338
Full Name sodium channel, non-voltage-gated 1, beta subunit
Synonyms BESC1, ENaCb, ENaCbeta, SCNEB
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p12.2-p12.1

Summary Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009].
Disorder

MIM: 600760

Liddle syndrome, 177200 (3); Pseudohypoaldosteronism, type I, 264350

mRNA Protein Product Sequence Price Select
NM_000336, 124301195 NP_000327, 124301196 amiloride-sensitive sodium channel subunit beta ORF Sequence $700.00
XM_005255467, 530408653 XP_005255524, 530408654 amiloride-sensitive sodium channel subunit beta isoform X1 ORF Sequence $700.00
KEGG
hsa04742Taste transduction
hsa04960Aldosterone-regulated sodium reabsorption
Reactome
REACT_15518Transmembrane transport of small molecules
REACT_25300Ion channel transport
REACT_160189Stimuli-sensing channels
Homo sapiens (human)SCNN1BNP_000327.2
Pan troglodytes (chimpanzee)SCNN1BXP_001161438.2
Macaca mulatta (Rhesus monkey)SCNN1BXP_001093933.1
Canis lupus familiaris (dog)SCNN1BXP_005621478.1
Bos taurus (cattle)SCNN1BNP_001091544.1
Mus musculus (house mouse)Scnn1bNP_035455.1
Rattus norvegicus (Norway rat)Scnn1bNP_036780.1
Gallus gallus (chicken)SCNN1BXP_425247.3
Xenopus (Silurana) tropicalis (western clawed frog)scnn1bNP_001072437.1
Process
IDNameEvidence
GO:0006814sodium ion transportTAS
GO:0007588excretionTAS
GO:0034220ion transmembrane transportTAS
GO:0035725sodium ion transmembrane transportIDA
GO:0050891multicellular organismal water homeostasisIDA
GO:0050896response to stimulusIEA
GO:0050909sensory perception of tasteIEA
GO:0055078sodium ion homeostasisIDA
GO:0055085transmembrane transportTAS
Component
IDNameEvidence
GO:0005886plasma membraneTAS
GO:0005887integral component of plasma membraneIDA
GO:0009897external side of plasma membraneIEA
GO:0016324apical plasma membraneIEA
GO:0034706sodium channel complexIDA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0015280ligand-gated sodium channel activityIDA
GO:0050699WW domain bindingIPI
GeneCards SCNN1B
UniProt P51168, B2R812
Vega OTTHUMG00000131608
MIM 600760
Ensembl ENSG00000168447
HGNC 10600
HPRD 02861

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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