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CCL4 chemokine (C-C motif) ligand 4 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_002984 Homo sapiens chemokine (C-C motif) ligand 4 (CCL4), mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10

*Business Day

Related Services

Gene Symbol CCL4
Entrez Gene ID 6351
Full Name chemokine (C-C motif) ligand 4
Synonyms ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4
General protein information
Preferred Names
C-C motif chemokine 4
Names
C-C motif chemokine 4
PAT 744
SIS-gamma
MIP-1-beta(1-69)
secreted protein G-26
T-cell activation protein 2
G-26 T-lymphocyte-secreted protein
lymphocyte activation gene 1 protein
macrophage inflammatory protein 1-beta
small inducible cytokine A4 (homologous to mouse Mip-1b)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q12

Summary The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012].
Disorder

MIM: 182284

mRNA Protein Product Sequence Price Select
NM_002984, 90704850 NP_002975, 4506845 C-C motif chemokine 4 precursor ORF Sequence $99.00
KEGG
hsa04060Cytokine-cytokine receptor interaction
hsa04620Toll-like receptor signaling pathway
hsa04062Chemokine signaling pathway
hsa04623Cytosolic DNA-sensing pathway
hsa05132Salmonella infection
hsa04064NF-kappa B signaling pathway
WikiPathways
WP75Toll-like receptor signaling pathway
WP1449Regulation of toll-like receptor signaling pathway
Pathway Interaction Database
il12_2pathwayIL12-mediated signaling events
Reactome
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_15344Chemokine receptors bind chemokines
REACT_14797Signaling by GPCR
REACT_14819Peptide ligand-binding receptors
REACT_21340GPCR ligand binding
REACT_111102Signal Transduction
Homo sapiens (human)CCL4NP_002975.1
Pan troglodytes (chimpanzee)CCL4XP_001173914.1
Macaca mulatta (Rhesus monkey)CCL4L1NP_001028045.1
Macaca mulatta (Rhesus monkey)LOC100430627XP_002800427.1
Macaca mulatta (Rhesus monkey)LOC100426632XP_002800713.1
Macaca mulatta (Rhesus monkey)LOC100423861XP_002800704.1
Canis lupus familiaris (dog)CCL4NP_001005250.1
Bos taurus (cattle)CCL4NP_001068615.1
Mus musculus (house mouse)Ccl4NP_038680.1
Rattus norvegicus (Norway rat)Ccl4NP_446310.1
Gallus gallus (chicken)CCL4NP_990051.1
Process
IDNameEvidence
GO:0006928cellular component movementTAS
GO:0006954inflammatory responseIEA
GO:0006955immune responseIEA
GO:0007155cell adhesionTAS
GO:0007163establishment or maintenance of cell polarityTAS
GO:0007165signal transductionTAS
GO:0007267cell-cell signalingTAS
GO:0009615response to virusTAS
GO:0009636response to toxic substanceIDA
GO:0043922negative regulation by host of viral transcriptionIDA
GO:0050850positive regulation of calcium-mediated signalingIMP
GO:0051928positive regulation of calcium ion transportIDA
GO:0060326cell chemotaxisIEA
GO:0060326cell chemotaxisTAS
GO:2000503positive regulation of natural killer cell chemotaxisIDA
Component
IDNameEvidence
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIEA
Function
IDNameEvidence
GO:0005125cytokine activityTAS
GO:0005515protein bindingIPI
GO:0008009chemokine activityIEA
GO:0031726CCR1 chemokine receptor bindingIPI
GO:0031730CCR5 chemokine receptor bindingIPI
GO:0042802identical protein bindingIPI
GeneCards CCL4
MIM 182284
HGNC 10630
HPRD 01657

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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