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CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu16454 NM_002988 Homo sapiens chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) (CCL18), mRNA. pcDNA3.1+-DYK On-demand 7-9 $209.00
OHu16454C NM_002988 Homo sapiens chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) (CCL18), mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol CCL18
Entrez Gene ID 6362
Full Name chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
Synonyms AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18
General protein information
Preferred Names
C-C motif chemokine 18
Names
C-C motif chemokine 18
CC chemokine PARC
CC chemokine ligand 18
chemokine (C-C), dendritic
dendritic cell chemokine 1
small inducible cytokine A18
small-inducible cytokine A18
macrophage inflammatory protein 4
pulmonary and activation-regulated chemokine
alternative macrophage activation-associated CC chemokine 1
small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q11.2

Summary This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Jul 2008].
Disorder

MIM: 603757

mRNA Protein Product Sequence Price Select
NM_002988, 22547150 NP_002979, 4506831 C-C motif chemokine 18 precursor ORF Sequence $150.00
KEGG
hsa04060Cytokine-cytokine receptor interaction
hsa04062Chemokine signaling pathway
Homo sapiens (human)CCL18NP_002979.1
Pan troglodytes (chimpanzee)CCL18XP_523615.1
Macaca mulatta (Rhesus monkey)CCL18NP_001028025.1
Process
IDNameEvidence
GO:0006935chemotaxisTAS
GO:0006954inflammatory responseIEA
GO:0006955immune responseIEA
GO:0007154cell communicationTAS
GO:0007165signal transductionTAS
GO:0007267cell-cell signalingTAS
GO:0009607response to biotic stimulusTAS
GO:0060326cell chemotaxisIEA
GO:0060326cell chemotaxisTAS
Component
IDNameEvidence
GO:0005615extracellular spaceIEA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0008009chemokine activityIEA
GeneCards CCL18
UniProt P55774
MIM 603757
HGNC 10616
HPRD 04784

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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