CCL20 chemokine (C-C motif) ligand 20 [Homo sapiens (human)]
| Gene Symbol | CCL20 |
| Entrez Gene ID | 6364 |
| Full Name | chemokine (C-C motif) ligand 20 |
| Synonyms | CKb4, LARC, MIP-3a, MIP3A, SCYA20, ST38 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
2 2q33-q37 |
| Summary | |
| Disorder | MIM: 601960 |
| mRNA | NM_004591, 194239686 |
| Protein | NP_004582, 4759076 |
| Product | C-C motif chemokine 20 isoform 1 |
| RefSeq Status | VALIDATED |
| mRNA | NM_001130046, 194239687 |
| Protein | NP_001123518, 194239688 |
| Product | C-C motif chemokine 20 isoform 2 |
| RefSeq Status | VALIDATED |
| hsa05323 | Rheumatoid arthritis |
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04062 | Chemokine signaling pathway |
Reactome
| REACT_21340 | GPCR ligand binding |
| REACT_14819 | Peptide ligand-binding receptors |
| REACT_15344 | Chemokine receptors bind chemokines |
| REACT_14828 | Class A/1 (Rhodopsin-like receptors) |
| REACT_19231 | G alpha (i) signalling events |
| REACT_14797 | Signaling by GPCR |
| REACT_19184 | GPCR downstream signaling |
| Homo sapiens (human) | CCL20 | NP_004582.1 |
| Pan troglodytes (chimpanzee) | CCL20 | XP_516133.2 |
| Canis lupus familiaris (dog) | CCL20 | NP_001005254.1 |
| Bos taurus (cattle) | CCL20 | NP_776688.1 |
| Mus musculus (house mouse) | Ccl20 | NP_058656.1 |
| Rattus norvegicus (Norway rat) | Ccl20 | NP_062106.1 |
| Gallus gallus (chicken) | CCL20 | NP_989769.1 |
| ID | Name | Evidence |
| GO:0006935 | chemotaxis | IEA |
| GO:0006954 | inflammatory response | IEA |
| GO:0006955 | immune response | IEA |
| GO:0007165 | signal transduction | TAS |
| GO:0007267 | cell-cell signaling | TAS |
| GO:0042466 | chemokinesis | IEA |
| GO:0042742 | defense response to bacterium | IEA |
Component
| ID | Name | Evidence |
| GO:0005576 | extracellular region | EXP |
| GO:0005576 | extracellular region | TAS |
| GO:0005615 | extracellular space | IEA |
Function
| ID | Name | Evidence |
| GO:0008009 | chemokine activity | IEA |
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