CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) [Homo sapiens (human)]
| Gene Symbol | CXCL6 |
| Entrez Gene ID | 6372 |
| Full Name | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) |
| Synonyms | CKA-3, GCP-2, GCP2, SCYB6 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
4 4q21 |
| Summary | |
| Disorder | MIM: 138965 |
| mRNA | NM_002993, 194733730 |
| Protein | NP_002984, 4506851 |
| Product | C-X-C motif chemokine 6 |
| RefSeq Status | VALIDATED |
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04062 | Chemokine signaling pathway |
| hsa05323 | Rheumatoid arthritis |
Reactome
| REACT_14828 | Class A/1 (Rhodopsin-like receptors) |
| REACT_19231 | G alpha (i) signalling events |
| REACT_19184 | GPCR downstream signaling |
| REACT_15344 | Chemokine receptors bind chemokines |
| REACT_21340 | GPCR ligand binding |
| REACT_14819 | Peptide ligand-binding receptors |
| REACT_14797 | Signaling by GPCR |
| Homo sapiens (human) | CXCL6 | NP_002984.1 |
| Pan troglodytes (chimpanzee) | CXCL6 | XP_001156255.1 |
| Mus musculus (house mouse) | Cxcl5 | NP_033167.2 |
| Rattus norvegicus (Norway rat) | Cxcl6 | XP_001068757.1 |
| ID | Name | Evidence |
| GO:0006935 | chemotaxis | IEA |
| GO:0006954 | inflammatory response | TAS |
| GO:0006955 | immune response | IEA |
| GO:0007165 | signal transduction | TAS |
| GO:0007267 | cell-cell signaling | TAS |
Component
| ID | Name | Evidence |
| GO:0005576 | extracellular region | EXP |
| GO:0005576 | extracellular region | TAS |
| GO:0005615 | extracellular space | IEA |
Function
| ID | Name | Evidence |
| GO:0008009 | chemokine activity | IEA |
| GO:0008201 | heparin binding | IEA |
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