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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


CX3CL1 chemokine (C-X3-C motif) ligand 1 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu23577 NM_002996 Homo sapiens chemokine (C-X3-C motif) ligand 1 (CX3CL1), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu23577C NM_002996 Homo sapiens chemokine (C-X3-C motif) ligand 1 (CX3CL1), mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol CX3CL1
Entrez Gene ID 6376
Full Name chemokine (C-X3-C motif) ligand 1
Synonyms ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin
General protein information
Preferred Names
fractalkine
Names
fractalkine
C-X3-C motif chemokine 1
small-inducible cytokine D1
CX3C membrane-anchored chemokine
small inducible cytokine subfamily D (Cys-X3-Cys), member-1
small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16q13

Summary
Disorder

MIM: 601880

mRNA Protein Product Sequence Price Select
NM_002996, 54111253 NP_002987, 4506857 fractalkine precursor ORF Sequence $269.00
KEGG
hsa04060Cytokine-cytokine receptor interaction
hsa04062Chemokine signaling pathway
hsa04668TNF signaling pathway
Pathway Interaction Database
p53downstreampathwayDirect p53 effectors
Reactome
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_15344Chemokine receptors bind chemokines
REACT_14797Signaling by GPCR
REACT_14819Peptide ligand-binding receptors
REACT_21340GPCR ligand binding
REACT_111102Signal Transduction
Homo sapiens (human)CX3CL1NP_002987.1
Pan troglodytes (chimpanzee)CX3CL1XP_510989.2
Macaca mulatta (Rhesus monkey)CX3CL1NP_001028053.1
Canis lupus familiaris (dog)CX3CL1XP_005617579.1
Bos taurus (cattle)CX3CL1XP_002694931.1
Mus musculus (house mouse)Cx3cl1NP_033168.2
Rattus norvegicus (Norway rat)Cx3cl1NP_604450.1
Process
IDNameEvidence
GO:0006935chemotaxisIDA
GO:0006952defense responseTAS
GO:0006955immune responseTAS
GO:0007155cell adhesionIEA
GO:0019221cytokine-mediated signaling pathwayTAS
GO:0030593neutrophil chemotaxisIEA
GO:0030595leukocyte chemotaxisTAS
GO:0032914positive regulation of transforming growth factor beta1 productionIEA
GO:0045766positive regulation of angiogenesisIEA
GO:0048246macrophage chemotaxisIEA
GO:0048247lymphocyte chemotaxisIEA
GO:0050729positive regulation of inflammatory responseIEP
GO:0050902leukocyte adhesive activationTAS
GO:0051041positive regulation of calcium-independent cell-cell adhesionIDA
GO:0060055angiogenesis involved in wound healingIEA
GO:2001240negative regulation of extrinsic apoptotic signaling pathway in absence of ligandIEA
Component
IDNameEvidence
GO:0005576extracellular regionIDA
GO:0005615extracellular spaceIEA
GO:0005886plasma membraneTAS
GO:0009986cell surfaceIDA
GO:0016021integral component of membraneIDA
Function
IDNameEvidence
GO:0005102receptor bindingTAS
GO:0005515protein bindingIPI
GO:0008009chemokine activityIDA
GO:0008009chemokine activityTAS
GeneCards CX3CL1
PDB 3ONA, 1B2T, 1F2L
UniProt P78423, A0N0N7
Vega OTTHUMG00000133469
MIM 601880
Ensembl ENSG00000006210
HGNC 10647
HPRD 03529

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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