• THAT   AND

Sequence in raw or FASTA format:


Blast Method:


SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_003000 Homo sapiens succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB), nuclear gene encoding mitochondrial protein, mRNA. GenEZ ORF Cloning On-demand $449.00 14

*Business Day

Related Services

Gene Symbol SDHB
Entrez Gene ID 6390
Full Name succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Synonyms FLJ92337, IP, PGL4, SDH, SDH1, SDH2, SDHIP
Gene Type protein-coding
Organism Homo sapiens (human)



Summary Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008].

MIM: 185470

Paraganglioma, familial chromaffin, 4, 115310 (3); Pheochromocytoma,

mRNA Protein Product Sequence Price Select
NM_003000, 115387093 NP_002991, 115387094 succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor ORF Sequence $300.00
hsa05012Parkinson's disease
hsa_M00148Succinate dehydrogenase (ubiquinone)
hsa05010Alzheimer's disease
hsa_M00011Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
hsa00190Oxidative phosphorylation
hsa00020Citrate cycle (TCA cycle)
hsa05016Huntington's disease
WP78TCA Cycle
WP111Electron Transport Chain
HUMAN_PWY-5690TCA cycle II (eukaryotic)
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
REACT_1785Citric acid cycle (TCA cycle)
REACT_22393Respiratory electron transport
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_6305Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
Homo sapiens (human)SDHBNP_002991.2
Pan troglodytes (chimpanzee)SDHBXP_001155516.1
Macaca mulatta (Rhesus monkey)SDHBXP_001088349.1
Canis lupus familiaris (dog)SDHBNP_001239146.1
Bos taurus (cattle)SDHBNP_001035573.1
Mus musculus (house mouse)SdhbNP_075863.2
Rattus norvegicus (Norway rat)SdhbNP_001094009.1
Gallus gallus (chicken)LOC100859720XP_003642552.1
Gallus gallus (chicken)SDHBNP_001074344.1
Danio rerio (zebrafish)sdhbNP_001092210.1
Drosophila melanogaster (fruit fly)SdhBNP_477101.1
Caenorhabditis eleganssdhb-1NP_495992.1
Arabidopsis thaliana (thale cress)SDH2-3NP_680465.2
GeneCards SDHB
UniProt P21912
MIM 185470
Ensembl ENSG00000117118
HGNC 10681
HPRD 01707

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
iron-sulfur subunit of complex II


Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.