DPEP3 dipeptidase 3 [Homo sapiens (human)]
| Gene Symbol | DPEP3 |
| Entrez Gene ID | 64180 |
| Full Name | dipeptidase 3 |
| Synonyms | MBD3 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
16 16q22.1 |
| Summary | This gene encodes a membrane-bound glycoprotein from the family of dipeptidases involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family. Alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq]. |
| Disorder | MIM: 609926 |
| mRNA | NM_022357, 193211607 |
| Protein | NP_071752, 193211608 |
| Product | dipeptidase 3 isoform a |
| RefSeq Status | REVIEWED |
| mRNA | NM_001129758, 193211609 |
| Protein | NP_001123230, 193211610 |
| Product | dipeptidase 3 isoform b |
| RefSeq Status | REVIEWED |
| Homo sapiens (human) | DPEP3 | NP_071752.3 |
| Pan troglodytes (chimpanzee) | DPEP3 | XP_523398.2 |
| Canis lupus familiaris (dog) | DPEP3 | XP_546868.2 |
| Bos taurus (cattle) | DPEP3 | XP_875681.2 |
| Mus musculus (house mouse) | Dpep3 | NP_082236.1 |
| Rattus norvegicus (Norway rat) | Dpep3 | NP_001008384.1 |
| Drosophila melanogaster (fruit fly) | CG42400 | NP_724101.3 |
| ID | Name | Evidence |
| GO:0006508 | proteolysis | IEA |
| GO:0007126 | meiosis | IEA |
Component
| ID | Name | Evidence |
| GO:0005624 | membrane fraction | IEA |
| GO:0016020 | membrane | IEA |
| GO:0031225 | anchored to membrane | IEA |
Function
| ID | Name | Evidence |
| GO:0008233 | peptidase activity | IEA |
| GO:0008235 | metalloexopeptidase activity | IEA |
| GO:0008239 | dipeptidyl-peptidase activity | IEA |
| GO:0016805 | dipeptidase activity | IEA |
| GO:0046872 | metal ion binding | IEA |
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