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ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_022436 Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 5 (ABCG5), mRNA. GenEZ ORF Cloning In-stock $639.00 $590.00 15

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Gene Symbol ABCG5
Entrez Gene ID 64240
Full Name ATP-binding cassette, sub-family G (WHITE), member 5
Synonyms STSL
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].

MIM: 605459

Sitosterolemia, 210250 (3)

mRNA Protein Product Sequence Price Select
NM_022436, 14141174 NP_071881, 11967969 ATP-binding cassette sub-family G member 5 ORF Sequence $490.00
hsa04976Bile secretion
hsa02010ABC transporters
hsa04975Fat digestion and absorption
WP716Vitamin A and carotenoid metabolism
WP299Nuclear receptors in lipid metabolism and toxicity
WP430Statin Pathway
REACT_22258Metabolism of lipids and lipoproteins
REACT_111158ABCA transporters in lipid homeostasis
REACT_15480ABC-family proteins mediated transport
REACT_15518Transmembrane transport of small molecules
REACT_602Lipid digestion, mobilization, and transport
REACT_13781Trafficking of dietary sterols
Homo sapiens (human)ABCG5NP_071881.1
Pan troglodytes (chimpanzee)ABCG5XP_003309098.1
Macaca mulatta (Rhesus monkey)ABCG5XP_001111277.1
Canis lupus familiaris (dog)ABCG5XP_538475.1
Bos taurus (cattle)ABCG5NP_001019718.1
Mus musculus (house mouse)Abcg5NP_114090.1
Rattus norvegicus (Norway rat)Abcg5NP_446206.2
Gallus gallus (chicken)ABCG5XP_419457.3
Danio rerio (zebrafish)abcg5NP_001122162.1
Drosophila melanogaster (fruit fly)CG11069NP_651307.2
GeneCards ABCG5
UniProt Q9H222
MIM 605459
Ensembl ENSG00000138075
HGNC 13886
HPRD 05678

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
ATP-binding cassette sub-family G member 5
ATP-binding cassette sub-family G member 5
sterolin 1
ATP-binding cassette, subfamily G, member 5


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