• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


SFTPB surfactant protein B [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu09313 NM_000542 Homo sapiens surfactant protein B (SFTPB), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu09313 NM_198843 Homo sapiens surfactant protein B (SFTPB), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu09313 XM_005264487 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu35551 XM_005264488 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu35551 XM_005264489 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu35552 XM_005264490 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu35553 XM_006712076 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu09313C NM_000542 Homo sapiens surfactant protein B (SFTPB), transcript variant 1, mRNA. Customized vector On-demand 7-9 $269.00
OHu09313C NM_198843 Homo sapiens surfactant protein B (SFTPB), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00
OHu09313C XM_005264487 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X1, mRNA. Customized vector On-demand 7-9 $269.00
OHu35551C XM_005264488 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X2, mRNA. Customized vector On-demand 7-9 $269.00
OHu35551C XM_005264489 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X3, mRNA. Customized vector On-demand 7-9 $269.00
OHu35552C XM_005264490 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X4, mRNA. Customized vector On-demand 7-9 $269.00
OHu35553C XM_006712076 PREDICTED: Homo sapiens surfactant protein B (SFTPB), transcript variant X5, mRNA. Customized vector On-demand 7-9 $209.00

*Business Day

Related Services

Gene Symbol SFTPB
Entrez Gene ID 6439
Full Name surfactant protein B
Synonyms PSP-B, SFTB3, SFTP3, SMDP1, SP-B
General protein information
Preferred Names
pulmonary surfactant-associated protein B
Names
pulmonary surfactant-associated protein B
6 kDa protein
18 kDa pulmonary-surfactant protein
pulmonary surfactant-associated proteolipid SPL(Phe)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p12-p11.2

Summary This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010].
Disorder

MIM: 178640

Surfactant metabolism dysfunction, pulmonary, 1, 265120 (3)

mRNA Protein Product Sequence Price Select
NM_000542, 288856298 NP_000533, 288856299 pulmonary surfactant-associated protein B precursor ORF Sequence $400.00
NM_198843, 288856296 NP_942140, 288856297 pulmonary surfactant-associated protein B precursor ORF Sequence $400.00
XM_005264487, 530367949 XP_005264544, 530367950 pulmonary surfactant-associated protein B isoform X1 ORF Sequence $400.00
XM_005264488, 530367951 XP_005264545, 530367952 pulmonary surfactant-associated protein B isoform X2 ORF Sequence $400.00
XM_005264489, 530367953 XP_005264546, 530367954 pulmonary surfactant-associated protein B isoform X3 ORF Sequence $400.00
XM_005264490, 578803094 XP_005264547, 530367956 pulmonary surfactant-associated protein B isoform X4 ORF Sequence $400.00
XM_006712076, 578803095 XP_006712139, 578803096 pulmonary surfactant-associated protein B isoform X5 ORF Sequence $300.00
Homo sapiens (human)SFTPBNP_000533.3
Pan troglodytes (chimpanzee)SFTPBXP_001168379.2
Macaca mulatta (Rhesus monkey)SFTPBXP_001089841.1
Canis lupus familiaris (dog)SFTPBXP_005630540.1
Bos taurus (cattle)SFTPBNP_001068779.1
Mus musculus (house mouse)SftpbNP_001269000.1
Rattus norvegicus (Norway rat)SftpbNP_620197.1
Xenopus (Silurana) tropicalis (western clawed frog)sftpbXP_002932589.2
Process
IDNameEvidence
GO:0006665sphingolipid metabolic processIEA
GO:0007585respiratory gaseous exchangeIEA
GO:0009887organ morphogenesisTAS
Component
IDNameEvidence
GO:0005615extracellular spaceIEA
GO:0005764lysosomeIEA
GeneCards SFTPB
PDB 2M1T, 1RG3, 1RG4, 2M0H, 1SSZ, 1DFW, 1KMR, 2DWF, 2JOU
UniProt P07988, D6W5L6
Vega OTTHUMG00000130181
MIM 178640
Ensembl ENSG00000168878
HGNC 10801
HPRD 01523

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.