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SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000023 Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10
NM_001135697 Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $449.00 14

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Gene Symbol SGCA
Entrez Gene ID 6442
Full Name sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
Synonyms 50-DAG, A2, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

MIM: 600119

Muscular dystrophy, limb-girdle, type 2D, 608099 (3); Adhalinopathy,

mRNA Protein Product Sequence Price Select
NM_000023, 208973224 NP_000014, 4506911 alpha-sarcoglycan isoform 1 precursor ORF Sequence $269.00
NM_001135697, 208973225 NP_001129169, 208973226 alpha-sarcoglycan isoform 2 precursor ORF Sequence $300.00
hsa05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa05416Viral myocarditis
hsa05414Dilated cardiomyopathy
WP2118Arrhythmogenic right ventricular cardiomyopathy
Homo sapiens (human)SGCANP_000014.1
Pan troglodytes (chimpanzee)SGCAXP_523792.2
Macaca mulatta (Rhesus monkey)SGCAXP_001092850.1
Canis lupus familiaris (dog)SGCAXP_851587.2
Bos taurus (cattle)SGCANP_001013420.1
Mus musculus (house mouse)SgcaNP_033187.1
Rattus norvegicus (Norway rat)SgcaNP_001100509.1
Danio rerio (zebrafish)im:7165146XP_685270.2
GeneCards SGCA
UniProt Q16586
MIM 600119
Ensembl ENSG00000108823
HGNC 10805
HPRD 02525

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
50kD DAG
50 kDa dystrophin-associated glycoprotein


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