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Sequence in raw or FASTA format:

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SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu19381 NM_000023 Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu31407 NM_001135697 Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu50583 XM_006722014 PREDICTED: Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu50584 XM_005257574 PREDICTED: Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu19381C NM_000023 Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00
OHu31407C NM_001135697 Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant 2, mRNA. Customized vector On-demand 7-9 $209.00
OHu50583C XM_006722014 PREDICTED: Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant X2, mRNA. Customized vector On-demand 7-9 $269.00
OHu50584C XM_005257574 PREDICTED: Homo sapiens sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant X1, mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol SGCA
Entrez Gene ID 6442
Full Name sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
Synonyms 50-DAG, A2, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin
General protein information
Preferred Names
alpha-sarcoglycan
Names
alpha-sarcoglycan
50DAG
50kD DAG
alpha-SG
dystroglycan-2
50 kDa dystrophin-associated glycoprotein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q21

Summary This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
Disorder

MIM: 600119

Muscular dystrophy, limb-girdle, type 2D, 608099 (3); Adhalinopathy,

mRNA Protein Product Sequence Price Select
NM_000023, 208973224 NP_000014, 4506911 alpha-sarcoglycan isoform 1 precursor ORF Sequence $269.00
NM_001135697, 208973225 NP_001129169, 208973226 alpha-sarcoglycan isoform 2 precursor ORF Sequence $300.00
XM_005257574, 530412661 XP_005257631, 530412662 alpha-sarcoglycan isoform X1 ORF Sequence $300.00
XM_006722014, 578831242 XP_006722077, 578831243 alpha-sarcoglycan isoform X2 ORF Sequence $400.00
KEGG
hsa05416Viral myocarditis
hsa05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa05414Dilated cardiomyopathy
hsa05410Hypertrophic cardiomyopathy (HCM)
WikiPathways
WP2118Arrhythmogenic right ventricular cardiomyopathy
Homo sapiens (human)SGCANP_000014.1
Pan troglodytes (chimpanzee)SGCAXP_523792.2
Macaca mulatta (Rhesus monkey)SGCAXP_001092850.1
Canis lupus familiaris (dog)SGCAXP_005624692.1
Bos taurus (cattle)SGCANP_001013420.1
Mus musculus (house mouse)SgcaNP_033187.1
Rattus norvegicus (Norway rat)SgcaNP_001100509.1
Xenopus (Silurana) tropicalis (western clawed frog)sgcaXP_002935590.2
Process
IDNameEvidence
GO:0006936muscle contractionIEA
GO:0007517muscle organ developmentIEA
Component
IDNameEvidence
GO:0005737cytoplasmIEA
GO:0005856cytoskeletonIEA
GO:0005911cell-cell junctionIEA
GO:0016010dystrophin-associated glycoprotein complexTAS
GO:0016012sarcoglycan complexIEA
GO:0016021integral component of membraneIEA
GO:0042383sarcolemmaIEA
GO:0045121membrane raftIEA
Function
IDNameEvidence
GO:0005509calcium ion bindingIEA
GeneCards SGCA
UniProt Q16586
Vega OTTHUMG00000162024
MIM 600119
Ensembl ENSG00000108823
HGNC 10805
HPRD 02525

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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