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Sequence in raw or FASTA format:

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TMPRSS3 transmembrane protease, serine 3 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001256317 Homo sapiens transmembrane protease, serine 3 (TMPRSS3), transcript variant F, mRNA. ORF Sequence $394.98
Peptide Services
Antibody Services
Protein Services
NM_024022 Homo sapiens transmembrane protease, serine 3 (TMPRSS3), transcript variant A, mRNA. ORF Sequence $395.85
Peptide Services
Antibody Services
Protein Services
NM_032404 Homo sapiens transmembrane protease, serine 3 (TMPRSS3), transcript variant C, mRNA. ORF Sequence $285.36
Peptide Services
Antibody Services
Protein Services
NM_032405 Homo sapiens transmembrane protease, serine 3 (TMPRSS3), transcript variant D, mRNA. ORF Sequence $300.15
Peptide Services
Antibody Services
Protein Services


Gene Symbol TMPRSS3
Entrez Gene ID 64699
Full Name transmembrane protease, serine 3
Synonyms DFNB10, DFNB8, ECHOS1, TADG12
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

21

21q22.3

Summary This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012].
Disorder

MIM: 605511

Deafness, autosomal recessive 8, childhood onset, 601072 (3);

mRNA Protein Product Sequence Price Select
NM_001256317, 373251165 NP_001243246, 373251166 transmembrane protease serine 3 isoform 4 Full Length $713.40
ORF Sequence $394.98
NM_024022, 224994254 NP_076927, 13173471 transmembrane protease serine 3 isoform 1 Full Length $714.27
ORF Sequence $395.85
NM_032404, 373222560 NP_115780, 14602455 transmembrane protease serine 3 isoform 2 Full Length $626.69
ORF Sequence $285.36
NM_032405, 14602456 NP_115781, 14602457 transmembrane protease serine 3 isoform 3 Full Length $394.11
ORF Sequence $300.15
Homo sapiens (human)TMPRSS3NP_076927.1
Pan troglodytes (chimpanzee)TMPRSS3XP_001137100.3
Macaca mulatta (Rhesus monkey)TMPRSS3XP_001105841.2
Canis lupus familiaris (dog)TMPRSS3XP_853682.2
Bos taurus (cattle)TMPRSS3NP_001179855.1
Mus musculus (house mouse)Tmprss3NP_001157248.1
Rattus norvegicus (Norway rat)Tmprss3NP_001101089.1
Gallus gallus (chicken)TMPRSS3XP_425558.2
Drosophila melanogaster (fruit fly)CG3355NP_608848.1
Drosophila melanogaster (fruit fly)CG4613NP_648707.1
GeneCards TMPRSS3
UniProt P57727
MIM 605511
Ensembl ENSG00000160183
HGNC 11877
HPRD 05696

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
transmembrane protease serine 3
Names
transmembrane protease serine 3
serine protease TADG-12
tumor-associated differentially-expressed gene 12 protein
NP_001243246.1
NP_076927.1
NP_115780.1
NP_115781.1

Interactant

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