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SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu14697 NM_001278659 Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu20407 NM_000340 Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu21696 NM_001278658 Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu14697C NM_001278659 Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2), transcript variant 3, mRNA. Customized vector On-demand 7-9 $269.00
OHu20407C NM_000340 Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00
OHu21696C NM_001278658 Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol SLC2A2
Entrez Gene ID 6514
Full Name solute carrier family 2 (facilitated glucose transporter), member 2
Synonyms GLUT2
General protein information
Preferred Names
solute carrier family 2, facilitated glucose transporter member 2
Names
solute carrier family 2, facilitated glucose transporter member 2
glucose transporter type 2, liver
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3q26.1-q26.2

Summary This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013].
Disorder

MIM: 138160

{Diabetes mellitus, noninsulin-dependent} (3); Fanconi-Bickel

mRNA Protein Product Sequence Price Select
NM_000340, 4557850 NP_000331, 4557851 solute carrier family 2, facilitated glucose transporter member 2 isoform 1 ORF Sequence $360.00
NM_001278658, 522020365 NP_001265587, 522020366 solute carrier family 2, facilitated glucose transporter member 2 isoform 2 ORF Sequence $400.00
NM_001278659, 522020363 NP_001265588, 522020364 solute carrier family 2, facilitated glucose transporter member 2 isoform 3 ORF Sequence $400.00
KEGG
hsa04930Type II diabetes mellitus
hsa04950Maturity onset diabetes of the young
hsa04973Carbohydrate digestion and absorption
hsa04917Prolactin signaling pathway
hsa04911Insulin secretion
WikiPathways
WP534Glycolysis and Gluconeogenesis
WP1584Type II diabetes mellitus
Pathway Interaction Database
hnf3bpathwayFOXA2 and FOXA3 transcription factor networks
Reactome
REACT_19118SLC-mediated transmembrane transport
REACT_19343Facilitative Na+-independent glucose transporters
REACT_19305Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
REACT_18325Regulation of insulin secretion
REACT_212Glucose transport
REACT_9441Hexose transport
REACT_1505Integration of energy metabolism
REACT_474Metabolism of carbohydrates
REACT_13698Regulation of beta-cell development
REACT_15518Transmembrane transport of small molecules
REACT_13819Regulation of gene expression in beta cells
REACT_111217Metabolism
REACT_111045Developmental Biology
REACT_116125Disease
REACT_200783Myoclonic epilepsy of Lafora
REACT_200833Glycogen storage diseases
Homo sapiens (human)SLC2A2NP_000331.1
Pan troglodytes (chimpanzee)SLC2A2XP_516875.2
Macaca mulatta (Rhesus monkey)SLC2A2XP_001088382.1
Canis lupus familiaris (dog)SLC2A2XP_545289.3
Bos taurus (cattle)SLC2A2NP_001096692.1
Mus musculus (house mouse)Slc2a2NP_112474.2
Rattus norvegicus (Norway rat)Slc2a2NP_037011.2
Gallus gallus (chicken)SLC2A2NP_997061.1
Danio rerio (zebrafish)slc2a2NP_001036186.1
Xenopus (Silurana) tropicalis (western clawed frog)slc2a2NP_001011453.1
Process
IDNameEvidence
GO:0005975carbohydrate metabolic processTAS
GO:0006112energy reserve metabolic processTAS
GO:0008645hexose transportTAS
GO:0015758glucose transportTAS
GO:0031018endocrine pancreas developmentTAS
GO:0035428hexose transmembrane transportTAS
GO:0044281small molecule metabolic processTAS
GO:0050796regulation of insulin secretionTAS
GO:0055085transmembrane transportTAS
GO:0070837dehydroascorbic acid transportIEA
Component
IDNameEvidence
GO:0005737cytoplasmIEA
GO:0005886plasma membraneTAS
GO:0005887integral component of plasma membraneTAS
GO:0005903brush borderIEA
GO:0016020membraneTAS
Function
IDNameEvidence
GO:0005355glucose transmembrane transporter activityEXP
GO:0015149hexose transmembrane transporter activityTAS
GO:0033300dehydroascorbic acid transporter activityIEA
GO:0055056D-glucose transmembrane transporter activityIEA
GeneCards SLC2A2
UniProt P11168, Q6PAU8
Vega OTTHUMG00000158997
MIM 138160
Ensembl ENSG00000163581
HGNC 11006
HPRD 00685

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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