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SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001042 Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4), mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12

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Gene Symbol SLC2A4
Entrez Gene ID 6517
Full Name solute carrier family 2 (facilitated glucose transporter), member 4
Synonyms GLUT4
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008].

MIM: 138190

{Diabetes mellitus, noninsulin-dependent}, 125853 (3)

mRNA Protein Product Sequence Price Select
NM_001042, 83722278 NP_001033, 4507011 solute carrier family 2, facilitated glucose transporter member 4 ORF Sequence $360.00
hsa04910Insulin signaling pathway
hsa04920Adipocytokine signaling pathway
hsa04930Type II diabetes mellitus
Pathway Interaction Database
arf6_traffickingpathwayArf6 trafficking events
insulin_glucose_pathwayInsulin-mediated glucose transport
pi3kciaktpathwayClass I PI3K signaling events mediated by Akt
WP1584Type II diabetes mellitus
WP534Glycolysis and Gluconeogenesis
WP481Insulin Signaling
WP1403AMPK signaling
REACT_11123Membrane Trafficking
REACT_19343Facilitative Na+-independent glucose transporters
REACT_111045Developmental Biology
REACT_147867Translocation of GLUT4 to the Plasma Membrane
REACT_474Metabolism of carbohydrates
REACT_9441Hexose transport
REACT_15518Transmembrane transport of small molecules
REACT_212Glucose transport
REACT_19305Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
REACT_27161Transcriptional Regulation of White Adipocyte Differentiation
REACT_19118SLC-mediated transmembrane transport
Homo sapiens (human)SLC2A4NP_001033.1
Pan troglodytes (chimpanzee)SLC2A4XP_001169794.1
Macaca mulatta (Rhesus monkey)SLC2A4XP_001107391.1
Canis lupus familiaris (dog)SLC2A4NP_001152799.1
Bos taurus (cattle)SLC2A4NP_777029.1
Mus musculus (house mouse)Slc2a4NP_033230.2
Rattus norvegicus (Norway rat)Slc2a4NP_036883.1
GeneCards SLC2A4
UniProt Q05BQ3, P14672
MIM 138190
Ensembl ENSG00000181856
HGNC 11009
HPRD 00688

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
solute carrier family 2, facilitated glucose transporter member 4
solute carrier family 2, facilitated glucose transporter member 4
insulin-responsive glucose transporter type 4
glucose transporter type 4, insulin-responsive


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