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Blast Method:


SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_003059 Homo sapiens solute carrier family 22 (organic cation/zwitterion transporter), member 4 (SLC22A4), mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006714675 PREDICTED: Homo sapiens solute carrier family 22 (organic cation/zwitterion transporter), member 4 (SLC22A4), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $549.00 14

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Gene Symbol SLC22A4
Entrez Gene ID 6583
Full Name solute carrier family 22 (organic cation/zwitterion transporter), member 4
Synonyms OCTN1
General protein information
Preferred Names
solute carrier family 22 member 4
solute carrier family 22 member 4
ET transporter
ergothioneine transporter
integral membrane transport protein
organic cation/carnitine transporter 1
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
Gene Type protein-coding
Organism Homo sapiens (human)



Summary Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent. [provided by RefSeq, Jul 2008].

MIM: 604190

{Rheumatoid arthritis, susceptibility to}, 180300 (3)

mRNA Protein Product Sequence Price Select
NM_003059, 24497489 NP_003050, 24497490 solute carrier family 22 member 4 ORF Sequence $550.00
XM_006714675, 578810506 XP_006714738, 578810507 solute carrier family 22 member 4 isoform X1 ORF Sequence $400.00
REACT_19118SLC-mediated transmembrane transport
REACT_19305Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
REACT_15518Transmembrane transport of small molecules
REACT_22345Organic cation/anion/zwitterion transport
REACT_22357Organic cation transport
Homo sapiens (human)SLC22A4NP_003050.2
Pan troglodytes (chimpanzee)SLC22A4XP_001163062.1
Macaca mulatta (Rhesus monkey)LOC710179XP_002804554.1
Canis lupus familiaris (dog)SLC22A4XP_005626572.1
Bos taurus (cattle)SLC22A4NP_001193918.1
Mus musculus (house mouse)Slc22a4NP_062661.1
Rattus norvegicus (Norway rat)Slc22a4NP_071606.1
Gallus gallus (chicken)SLC22A4NP_001139603.1
Danio rerio (zebrafish)LOC100000685XP_005170394.1
GO:0006641triglyceride metabolic processIEA
GO:0006814sodium ion transportIEA
GO:0007589body fluid secretionTAS
GO:0009437carnitine metabolic processIEA
GO:0015695organic cation transportTAS
GO:0015697quaternary ammonium group transportIDA
GO:0015879carnitine transportIDA
GO:0055085transmembrane transportTAS
GO:1902603carnitine transmembrane transportIDA
GO:1902603carnitine transmembrane transportIEA
GO:0005886plasma membraneIC
GO:0005886plasma membraneTAS
GO:0005887integral component of plasma membraneTAS
GO:0016324apical plasma membraneIDA
GO:0000166nucleotide bindingTAS
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0008513secondary active organic cation transmembrane transporter activityTAS
GO:0015226carnitine transmembrane transporter activityIDA
GO:0015293symporter activityIEA
GO:0015491cation:cation antiporter activityIDA
GO:0015651quaternary ammonium group transmembrane transporter activityIDA
GO:0030165PDZ domain bindingIPI
GeneCards SLC22A4
UniProt Q9H015
Vega OTTHUMG00000059648
MIM 604190
Ensembl ENSG00000197208
HGNC 10968
HPRD 09171

GeneRIFs: Gene References Into Functions What's a GeneRIF?


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