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SNAI2 snail homolog 2 (Drosophila) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_003068 Homo sapiens snail homolog 2 (Drosophila) (SNAI2), mRNA. GenEZ ORF Cloning In-stock $348.00 $299.00 10

*Business Day

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Gene Symbol SNAI2
Entrez Gene ID 6591
Full Name snail homolog 2 (Drosophila)
Synonyms MGC10182, SLUG, SLUGH1, WS2D
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q11

Summary This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602150

Waardenburg syndrome, type 2D, 608890 (3); Piebaldism, 172800 (3)

mRNA Protein Product Sequence Price Select
NM_003068, 324072669 NP_003059, 11276067 zinc finger protein SNAI2 ORF Sequence $199.00
KEGG
hsa04520Adherens junction
WikiPathways
WP2064Neural Crest Differentiation
Pathway Interaction Database
wnt_beta_catenin_pathwayRegulation of Wnt-mediated beta catenin signaling and target gene transcription
p53downstreampathwayDirect p53 effectors
kitpathwaySignaling events mediated by Stem cell factor receptor (c-Kit)
Homo sapiens (human)SNAI2NP_003059.1
Pan troglodytes (chimpanzee)SNAI2XP_519753.2
Macaca mulatta (Rhesus monkey)SNAI2XP_001101435.1
Canis lupus familiaris (dog)SNAI2NP_001091450.1
Bos taurus (cattle)SNAI2NP_001029710.1
Mus musculus (house mouse)Snai2NP_035545.1
Gallus gallus (chicken)SNAI2XP_419196.1
Danio rerio (zebrafish)snai2NP_001008581.1
Drosophila melanogaster (fruit fly)esgNP_476600.1
Caenorhabditis elegansK02D7.2NP_499902.2
GeneCards SNAI2
UniProt O43623
MIM 602150
Ensembl ENSG00000019549
HGNC 11094
HPRD 03689

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
zinc finger protein SNAI2
Names
zinc finger protein SNAI2
snail homolog 2
protein snail homolog 2
neural crest transcription factor SLUG
slug (chicken homolog), zinc finger protein

Interactant



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