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SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_003070 Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_139045 Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Related Services

Gene Symbol SMARCA2
Entrez Gene ID 6595
Full Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Synonyms BAF190, BRM, FLJ36757, MGC74511, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9p22.3

Summary The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600014

mRNA Protein Product Sequence Price Select
NM_003070, 48255899 NP_003061, 48255900 probable global transcription activator SNF2L2 isoform a ORF Sequence $2500.00
NM_139045, 48255897 NP_620614, 48255898 probable global transcription activator SNF2L2 isoform b ORF Sequence $2500.00
Pathway Interaction Database
e2f_pathwayE2F transcription factor network
ar_tf_pathwayRegulation of Androgen receptor activity
cmyb_pathwayC-MYB transcription factor network
Homo sapiens (human)SMARCA2NP_620614.2
Canis lupus familiaris (dog)SMARCA2XP_850159.1
Bos taurus (cattle)SMARCA2NP_001092585.1
Mus musculus (house mouse)Smarca2NP_035546.2
Rattus norvegicus (Norway rat)Smarca2NP_001004446.1
Gallus gallus (chicken)SMARCA2NP_990470.1
Danio rerio (zebrafish)smarca2NP_997881.1
GeneCards SMARCA2
PDB 2DAT
UniProt Q8N9Q1, Q56A76, P51531
MIM 600014
Ensembl ENSG00000080503
HGNC 11098
HPRD 02483

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
probable global transcription activator SNF2L2
Names
probable global transcription activator SNF2L2
BAF190B
SNF2-alpha
protein brahma homolog
SNF2/SWI2-like protein 2
BRG1-associated factor 190B
ATP-dependent helicase SMARCA2
sucrose nonfermenting 2-like protein 2
global transcription activator homologous sequence
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2

Interactant



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